Unilateral glaucoma in Sotos syndrome (cerebral gigantism)

Michael T. Yen, Steven J Gedde, John T. Flynn

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

PURPOSE: To report a patient with unilateral glaucoma associated with Sotos syndrome. Sotos syndrome (cerebral gigantism) is a disorder of growth and development with characteristic facial changes and normal endocrine function. Ocular manifestations may also include megalocornea, iris hypoplasia, cataracts, megalophthalmos, strabismus, nystagmus, and retinal dystrophy. METHODS: Case report. A 50 year-old man with the clinical features of Sotos syndrome presented with complaints of decreased vision in the left eye. RESULTS: Ophthalmologic examination revealed bilateral megalocornea, megalophthalmos, iris hypoplasia and transillumination defects, cataracts, and unilateral glaucoma. Intraocular pressure was lowered, and visual field loss was stabilized with topical medications. CONCLUSION: Sotos syndrome patients should be examined routinely to allow for early detection and treatment of potential ocular problems, including glaucoma. Copyright (C) 2000 Elsevier Science Inc.

Original languageEnglish
Pages (from-to)851-853
Number of pages3
JournalAmerican Journal of Ophthalmology
Volume130
Issue number6
DOIs
StatePublished - Dec 1 2000

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Sotos Syndrome
Glaucoma
Iris
Cataract
Eye Manifestations
Retinal Dystrophies
Transillumination
Strabismus
Visual Fields
Intraocular Pressure
Growth and Development

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Unilateral glaucoma in Sotos syndrome (cerebral gigantism). / Yen, Michael T.; Gedde, Steven J; Flynn, John T.

In: American Journal of Ophthalmology, Vol. 130, No. 6, 01.12.2000, p. 851-853.

Research output: Contribution to journalArticle

Yen, Michael T. ; Gedde, Steven J ; Flynn, John T. / Unilateral glaucoma in Sotos syndrome (cerebral gigantism). In: American Journal of Ophthalmology. 2000 ; Vol. 130, No. 6. pp. 851-853.
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