Abstract
PURPOSE: To report a patient with unilateral glaucoma associated with Sotos syndrome. Sotos syndrome (cerebral gigantism) is a disorder of growth and development with characteristic facial changes and normal endocrine function. Ocular manifestations may also include megalocornea, iris hypoplasia, cataracts, megalophthalmos, strabismus, nystagmus, and retinal dystrophy. METHODS: Case report. A 50 year-old man with the clinical features of Sotos syndrome presented with complaints of decreased vision in the left eye. RESULTS: Ophthalmologic examination revealed bilateral megalocornea, megalophthalmos, iris hypoplasia and transillumination defects, cataracts, and unilateral glaucoma. Intraocular pressure was lowered, and visual field loss was stabilized with topical medications. CONCLUSION: Sotos syndrome patients should be examined routinely to allow for early detection and treatment of potential ocular problems, including glaucoma. Copyright (C) 2000 Elsevier Science Inc.
| Original language | English |
|---|---|
| Pages (from-to) | 851-853 |
| Number of pages | 3 |
| Journal | American Journal of Ophthalmology |
| Volume | 130 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 2000 |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
Unilateral glaucoma in Sotos syndrome (cerebral gigantism). / Yen, Michael T.; Gedde, Steven J; Flynn, John T.
In: American Journal of Ophthalmology, Vol. 130, No. 6, 01.12.2000, p. 851-853.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Unilateral glaucoma in Sotos syndrome (cerebral gigantism)
AU - Yen, Michael T.
AU - Gedde, Steven J
AU - Flynn, John T.
PY - 2000/12/1
Y1 - 2000/12/1
N2 - PURPOSE: To report a patient with unilateral glaucoma associated with Sotos syndrome. Sotos syndrome (cerebral gigantism) is a disorder of growth and development with characteristic facial changes and normal endocrine function. Ocular manifestations may also include megalocornea, iris hypoplasia, cataracts, megalophthalmos, strabismus, nystagmus, and retinal dystrophy. METHODS: Case report. A 50 year-old man with the clinical features of Sotos syndrome presented with complaints of decreased vision in the left eye. RESULTS: Ophthalmologic examination revealed bilateral megalocornea, megalophthalmos, iris hypoplasia and transillumination defects, cataracts, and unilateral glaucoma. Intraocular pressure was lowered, and visual field loss was stabilized with topical medications. CONCLUSION: Sotos syndrome patients should be examined routinely to allow for early detection and treatment of potential ocular problems, including glaucoma. Copyright (C) 2000 Elsevier Science Inc.
AB - PURPOSE: To report a patient with unilateral glaucoma associated with Sotos syndrome. Sotos syndrome (cerebral gigantism) is a disorder of growth and development with characteristic facial changes and normal endocrine function. Ocular manifestations may also include megalocornea, iris hypoplasia, cataracts, megalophthalmos, strabismus, nystagmus, and retinal dystrophy. METHODS: Case report. A 50 year-old man with the clinical features of Sotos syndrome presented with complaints of decreased vision in the left eye. RESULTS: Ophthalmologic examination revealed bilateral megalocornea, megalophthalmos, iris hypoplasia and transillumination defects, cataracts, and unilateral glaucoma. Intraocular pressure was lowered, and visual field loss was stabilized with topical medications. CONCLUSION: Sotos syndrome patients should be examined routinely to allow for early detection and treatment of potential ocular problems, including glaucoma. Copyright (C) 2000 Elsevier Science Inc.
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U2 - 10.1016/S0002-9394(00)00640-1
DO - 10.1016/S0002-9394(00)00640-1
M3 - Article
C2 - 11124318
AN - SCOPUS:0034529797
VL - 130
SP - 851
EP - 853
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 6
ER -