[pyro]Glu Ser Gly NH 2 has been reported to release growth hormone (GH). Therefore, this tripeptide was injected iv at a dose of 600 μg into 10 men and women, 3 of whom had acromegaly. Plasma levels of GH, thyroid stimulating hormone, luteinizing hormone and follicle stimulating hormone were measured, but no consistent elevations were found. The results do not support the proposal that [pyro]Glu Ser Gly NH 2 is the GH releasing hormone.
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Clinical Biochemistry
- Biochemistry, medical