Ultrastructural studies of olivopontocerebellar atrophy

Carol Petito, M. N. Hart, R. S. Porro, K. M. Earle

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

Three cases of olivopontocerebellar atrophy, one of which included a cerebellar biopsy, were examined for ultrastructural changes. Degenerative changes were identified within the afferent cerebellar fibers and within the cerebellar neurons, especially the Purkinje cells. Although the majority of the degenerative alterations have been previously described in a variety of disease states, there were some findings that have not been previously reported, including unusual striped bodies and Lafora body inclusions within Purkinje dendrites. The relationship between OPCA and other diseases is discussed and a possible slow viral etiology is considered.

Original languageEnglish
Pages (from-to)503-522
Number of pages20
JournalJournal of Neuropathology and Experimental Neurology
Volume32
Issue number4
StatePublished - Dec 1 1973
Externally publishedYes

Fingerprint

Olivopontocerebellar Atrophies
Purkinje Cells
Inclusion Bodies
Dendrites
Biopsy
Neurons

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Neuroscience(all)

Cite this

Petito, C., Hart, M. N., Porro, R. S., & Earle, K. M. (1973). Ultrastructural studies of olivopontocerebellar atrophy. Journal of Neuropathology and Experimental Neurology, 32(4), 503-522.

Ultrastructural studies of olivopontocerebellar atrophy. / Petito, Carol; Hart, M. N.; Porro, R. S.; Earle, K. M.

In: Journal of Neuropathology and Experimental Neurology, Vol. 32, No. 4, 01.12.1973, p. 503-522.

Research output: Contribution to journalArticle

Petito, C, Hart, MN, Porro, RS & Earle, KM 1973, 'Ultrastructural studies of olivopontocerebellar atrophy', Journal of Neuropathology and Experimental Neurology, vol. 32, no. 4, pp. 503-522.
Petito, Carol ; Hart, M. N. ; Porro, R. S. ; Earle, K. M. / Ultrastructural studies of olivopontocerebellar atrophy. In: Journal of Neuropathology and Experimental Neurology. 1973 ; Vol. 32, No. 4. pp. 503-522.
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