Ultrasound velocity criteria for vertebral origin stenosis

Sebastian Koch, Jose G Romano, Hannah Park, Murtaza Amir, Alejandro M. Forteza

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

BACKGROUND Despite remaining an important cause of posterior circulation stroke, the non-invasive diagnosis of vertebral artery origin (VAo) stenosis is problematic. We here examine peak systolic velocity (PSV) criteria for the diagnosis of VAo stenosis and assess if the PSV ratio at the origin to the distal segments improves diagnostic accuracy. METHODS We performed a retrospective analysis of patients studied by catheter cerebral angiography and extracranial Duplex ultrasonography. The angiographic degree of stenosis, PSV at the VAo, proximal vertebral artery (VA1), and intra-foraminal (VA2) segment were recorded. We calculated the VAo/VA1 and VAo/VA2 PSV ratio. A receiver operator curve was obtained (ROC) and the area under the curve (AUC) was compared for three different diagnostic criteria: PSV VAo, VAo/VA1, and VAo/VA2 PSV ratio. RESULTS A total of 386 vertebral arteries were angiographically examined and VAo stenosis 50-99% was found in 36 (9%) vessels. The PSV VAo was the most accurate diagnostic parameter with an AUC.821 ±.052 (SE) (CI:.72,.92). A PSV of 114 cm/second maximized sensitivity (71%) and specificity (90%). CONCLUSION Our results support the use of PSV as a diagnostic criterion for VAo stenosis compared to a PSV ratio of VAo/V1 and VAo/V2. J Neuroimaging 2009;19:242-245.

Original languageEnglish
Pages (from-to)242-245
Number of pages4
JournalJournal of Neuroimaging
Volume19
Issue number3
DOIs
StatePublished - Jul 1 2009

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Vertebral Artery
Pathologic Constriction
Vertebrobasilar Insufficiency
Cerebral Angiography
Neuroimaging
Area Under Curve
Ultrasonography
Catheters
Stroke
Sensitivity and Specificity

Keywords

  • Doppler
  • Velocity thresholds
  • Vertebral origin stenosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology

Cite this

Ultrasound velocity criteria for vertebral origin stenosis. / Koch, Sebastian; Romano, Jose G; Park, Hannah; Amir, Murtaza; Forteza, Alejandro M.

In: Journal of Neuroimaging, Vol. 19, No. 3, 01.07.2009, p. 242-245.

Research output: Contribution to journalArticle

Koch, Sebastian ; Romano, Jose G ; Park, Hannah ; Amir, Murtaza ; Forteza, Alejandro M. / Ultrasound velocity criteria for vertebral origin stenosis. In: Journal of Neuroimaging. 2009 ; Vol. 19, No. 3. pp. 242-245.
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