Ultrasound-guided fine needle biopsy of the pancreas: smear cytology versus microhistology

Riccardo Lencioni, Paolo Bagnolesi, Anna Cilotti, Salvatore Mazzeo, Roberto Cioni, Giuditta Scuotri, Carlo Bartolozzi

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Percutaneous fine needle biopsy (FNB), under sonographic guidance, of local pancreatic lesions was studied by comparing the results of smear cytology (SC) with microhistology (MH) in 34 patients in whom both sampling procedures were carried out. MH suffered from a higher number of inadequate samples (retrieval rate: 94.1% SC, 85.3% MH), but reached a superior sensitivity rate as regard to the diagnosis of pancreatic malignancy (91.7% MH, 80.8% SC). Both samples obtained an absolute specificity rate (100%. A 96.3% sensitivity rate was obtained by combination of the two techniques in the absence of complications. Thus, the combined use of SC and MH in pancreatic fine needle biopsy was proven to be a safe and reliable procedure.

Original languageEnglish (US)
Pages (from-to)252-2571
Number of pages2320
JournalEuropean Radiology
Issue number3
StatePublished - May 1992


  • Fine needle biopsy
  • Pancreas
  • Pancreatic carcinoma
  • diagnosis
  • interventional procedures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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