Ultra-widefield imaging of posterior segment pathology in the setting of the Boston Keratoprosthesis

Daniel L. Kornberg, Nicolas A. Yannuzzi, Michael A. Klufas, Donald J. D'Amico, Anton Orlin, Szilárd Kiss

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Purpose: To evaluate the ability to visualize and document posterior segment pathology through the Boston keratoprosthesis (KPro) using the Optos P200Tx ultra-widefield (UWF) scanning laser ophthalmoscope. Methods: A retrospective chart review was conducted of patients who underwent Boston Type I keratoprosthesis implantation and who subsequently were imaged with an UWF system. Ultra-widefield images were reviewed to evaluate for vitreoretinal pathology and were compared with the clinical examination. Results: In this series of 10 patients (10 eyes), 100% of vitreoretinal pathology found on clinical examination was detectable using the Optos system. In 4 cases (40%), UWF imaging provided superior detection of pathology compared with the clinical examination by imaging through retroprosthetic membranes (3 cases) and by detection of a retinal detachment (one case). In 1 case (10%), B-scan ultrasonography was needed to characterize vitreoretinal pathology that could not be definitively distinguished on UWF imaging and was difficult to detect on clinical examination. Ultra-widefield imaging detected the following vitreoretinal pathologies in KPro eyes: retinal hemorrhage, epiretinal membrane, retinal detachment, proliferative diabetic retinopathy, and choroidal folds. Conclusion: Ultra-widefield imaging provides a high-resolution view of the posterior pole and periphery despite the limitations of imaging through the narrow optic of Boston Type I keratoprosthesis, and it may improve visualization through retroprosthetic membranes. Detection and documentation of vitreoretinal complications in the setting of a permanent keratoprosthesis may be enhanced using UWF imaging.

Original languageEnglish (US)
Pages (from-to)1101-1110
Number of pages10
Issue number6
StatePublished - Jun 1 2016
Externally publishedYes


  • Boston KPro
  • keratoprosthesis
  • KPro
  • Optos
  • ultra-widefield imaging
  • vitreoretinal surgery

ASJC Scopus subject areas

  • Ophthalmology


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