Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

Aizhu Tao, Kristen A. Peterson, Hong Jiang, Yilei Shao, Jianguang Zhong, Frank C. Carey, Elias P. Rosen, Jianhua Wang

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal-scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.

Original languageEnglish (US)
Pages (from-to)1623-1633
Number of pages11
JournalClinical Ophthalmology
Volume7
DOIs
StatePublished - Aug 9 2013

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Keywords

  • Complex
  • Full range
  • Ocular surface
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology

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