Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface

Aizhu Tao, Kristen A. Peterson, Hong Jiang, Yilei Shao, Jianguang Zhong, Frank C. Carey, Elias P. Rosen, Jianhua Wang

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We used a unique combination of four state-of-the-art technologies to achieve a high performance spectral domain optical coherence tomography system suitable for imaging the entire ocular surface. An ultra-high resolution, extended depth range, full-phase interferometry, and high-speed complementary metal-oxide semiconductor transistor camera detection provided unprecedented performance for the precise quantification of a wide range of the ocular surface. We demonstrated the feasibility of this approach by obtaining high-speed and high-resolution images of a model eye beyond the corneal-scleral junction. Surfaces determined from the images with a segmentation algorithm demonstrated excellent accuracy and precision.

Original languageEnglish
Pages (from-to)1623-1633
Number of pages11
JournalClinical Ophthalmology
Volume7
DOIs
StatePublished - Aug 9 2013

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Optical Coherence Tomography
Interferometry
Semiconductors
Oxides
Metals
Technology

Keywords

  • Complex
  • Full range
  • Ocular surface
  • Optical coherence tomography

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface. / Tao, Aizhu; Peterson, Kristen A.; Jiang, Hong; Shao, Yilei; Zhong, Jianguang; Carey, Frank C.; Rosen, Elias P.; Wang, Jianhua.

In: Clinical Ophthalmology, Vol. 7, 09.08.2013, p. 1623-1633.

Research output: Contribution to journalArticle

Tao, Aizhu ; Peterson, Kristen A. ; Jiang, Hong ; Shao, Yilei ; Zhong, Jianguang ; Carey, Frank C. ; Rosen, Elias P. ; Wang, Jianhua. / Ultra-high resolution and long scan depth optical coherence tomography with full-phase detection for imaging the ocular surface. In: Clinical Ophthalmology. 2013 ; Vol. 7. pp. 1623-1633.
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