Type 2 myocardial infarction: is it a geriatric syndrome?

Francesco Curcio, Gerardo Gerundo, Giuseppe Sasso, Veronica Panicara, Ilaria Liguori, Gianluca Testa, David Della-Morte, Gaetano Gargiulo, Gianluigi Galizia, Andrea Ungar, Francesco Cacciatore, Domenico Bonaduce, Pasquale Abete

Research output: Contribution to journalReview article


Type 2 myocardial infarctions (T2-MI) is a type of necrosis that results from reduced oxygen supply and/or increased demand secondary to other causes unrelated to acute coronary atherothrombosis. The development and implementation of sensitive and high-sensitivity cardiac necrosis marker and the age-related increase of comorbidity lead to a boost of the frequency of T2-MI. T2-MI is often a complication of a high degree of clinical frailty in older adults, emerging as a “geriatric syndrome”. Age-related non-cardiovascular causes may be the triggering factors and are strongly associated with the diagnosis, treatment, and prognosis of T2-MI. To date, there are no guidelines on management of this pathology in advancing age. Patient-centered approach and comprehensive geriatric assessment play a key role in the diagnosis, therapy and prognosis of geriatric patients with T2-MI.

Original languageEnglish (US)
Pages (from-to)759-768
Number of pages10
JournalAging Clinical and Experimental Research
Issue number5
StatePublished - May 1 2020



  • Comprehensive geriatric assessment
  • Geriatric syndrome
  • Type 2 myocardial infarction

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

Curcio, F., Gerundo, G., Sasso, G., Panicara, V., Liguori, I., Testa, G., Della-Morte, D., Gargiulo, G., Galizia, G., Ungar, A., Cacciatore, F., Bonaduce, D., & Abete, P. (2020). Type 2 myocardial infarction: is it a geriatric syndrome? Aging Clinical and Experimental Research, 32(5), 759-768. https://doi.org/10.1007/s40520-019-01452-8