Tympanic membrane breakdown after intratympanic injection of steroids in irradiated ears

Yisgav Shapira; Fred F. Telischi

doi:10.1097/01.mao.0000271672.56554.32

Tympanic membrane breakdown after intratympanic injection of steroids in irradiated ears

Yisgav Shapira, Fred F. Telischi

Otolaryngology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

OBJECTIVE: To describe a rare complication of intratympanic injection of steroids in susceptible ears. PATIENTS: We present two patients with a history of irradiation involving the injected ear. INTERVENTION: Therapeutic. MAIN OUTCOME MEASURE: Tympanic membrane condition after intratympanic injection of steroids. RESULTS: Total or near-total breakdown of the irradiated tympanic membrane. CONCLUSION: Tympanic membranes with an impaired wound-healing ability, together with exposure to intratympanic steroids, may be at risk for total or near-total breakdown.

Original language	English (US)
Pages (from-to)	499-500
Number of pages	2
Journal	Otology and Neurotology
Volume	28
Issue number	4
DOIs	https://doi.org/10.1097/01.mao.0000271672.56554.32
State	Published - Jun 1 2007

Keywords

Complications
Intratympanic injection
Intratympanic steroids
Radiation therapy
Tympanic membrane perforation

ASJC Scopus subject areas

Otorhinolaryngology
Neuroscience(all)

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10.1097/01.mao.0000271672.56554.32

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abstract = "OBJECTIVE: To describe a rare complication of intratympanic injection of steroids in susceptible ears. PATIENTS: We present two patients with a history of irradiation involving the injected ear. INTERVENTION: Therapeutic. MAIN OUTCOME MEASURE: Tympanic membrane condition after intratympanic injection of steroids. RESULTS: Total or near-total breakdown of the irradiated tympanic membrane. CONCLUSION: Tympanic membranes with an impaired wound-healing ability, together with exposure to intratympanic steroids, may be at risk for total or near-total breakdown.",

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AU - Telischi, Fred F.

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N2 - OBJECTIVE: To describe a rare complication of intratympanic injection of steroids in susceptible ears. PATIENTS: We present two patients with a history of irradiation involving the injected ear. INTERVENTION: Therapeutic. MAIN OUTCOME MEASURE: Tympanic membrane condition after intratympanic injection of steroids. RESULTS: Total or near-total breakdown of the irradiated tympanic membrane. CONCLUSION: Tympanic membranes with an impaired wound-healing ability, together with exposure to intratympanic steroids, may be at risk for total or near-total breakdown.

AB - OBJECTIVE: To describe a rare complication of intratympanic injection of steroids in susceptible ears. PATIENTS: We present two patients with a history of irradiation involving the injected ear. INTERVENTION: Therapeutic. MAIN OUTCOME MEASURE: Tympanic membrane condition after intratympanic injection of steroids. RESULTS: Total or near-total breakdown of the irradiated tympanic membrane. CONCLUSION: Tympanic membranes with an impaired wound-healing ability, together with exposure to intratympanic steroids, may be at risk for total or near-total breakdown.

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KW - Intratympanic steroids

KW - Radiation therapy

KW - Tympanic membrane perforation

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