Two for One

A Case Report of Intravenous Lipid Emulsion to Treat Local Anesthetic Systemic Toxicity in Term Pregnancy

Jonathan Dun-Chi Lin, Eellan Sivanesan, Terese T. Horlocker, Andres Missair

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Combined spinal-epidural (CSE) analgesia is a frequently used method of labor analgesia. Although it is considered safe and effective, CSE can be complicated by local anesthetic systemic toxicity (LAST), a potentially life-threatening condition. We present a case of LAST that developed in a primigravida 50 minutes after uneventful placement of a CSE. Her symptoms resolved within 10 minutes of administering intralipid emulsion. She subsequently underwent cesarean delivery under spinal anesthesia for failure to progress without sequelae in the mother or infant. LAST in pregnancy can occur at traditionally subthreshold dosing; anesthesiologists must be vigilant to ensure prompt and effective treatment.

Original languageEnglish (US)
Pages (from-to)235-237
Number of pages3
JournalA & A case reports
Volume8
Issue number9
DOIs
StatePublished - May 1 2017

Fingerprint

Intravenous Fat Emulsions
Local Anesthetics
Pregnancy
Epidural Analgesia
Spinal Anesthesia
Emulsions
Analgesia
Mothers
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Two for One : A Case Report of Intravenous Lipid Emulsion to Treat Local Anesthetic Systemic Toxicity in Term Pregnancy. / Dun-Chi Lin, Jonathan; Sivanesan, Eellan; Horlocker, Terese T.; Missair, Andres.

In: A & A case reports, Vol. 8, No. 9, 01.05.2017, p. 235-237.

Research output: Contribution to journalArticle

Dun-Chi Lin, Jonathan ; Sivanesan, Eellan ; Horlocker, Terese T. ; Missair, Andres. / Two for One : A Case Report of Intravenous Lipid Emulsion to Treat Local Anesthetic Systemic Toxicity in Term Pregnancy. In: A & A case reports. 2017 ; Vol. 8, No. 9. pp. 235-237.
@article{4f6ee6d38c0546098f4572b915b166e0,
title = "Two for One: A Case Report of Intravenous Lipid Emulsion to Treat Local Anesthetic Systemic Toxicity in Term Pregnancy",
abstract = "Combined spinal-epidural (CSE) analgesia is a frequently used method of labor analgesia. Although it is considered safe and effective, CSE can be complicated by local anesthetic systemic toxicity (LAST), a potentially life-threatening condition. We present a case of LAST that developed in a primigravida 50 minutes after uneventful placement of a CSE. Her symptoms resolved within 10 minutes of administering intralipid emulsion. She subsequently underwent cesarean delivery under spinal anesthesia for failure to progress without sequelae in the mother or infant. LAST in pregnancy can occur at traditionally subthreshold dosing; anesthesiologists must be vigilant to ensure prompt and effective treatment.",
author = "{Dun-Chi Lin}, Jonathan and Eellan Sivanesan and Horlocker, {Terese T.} and Andres Missair",
year = "2017",
month = "5",
day = "1",
doi = "10.1213/XAA.0000000000000477",
language = "English (US)",
volume = "8",
pages = "235--237",
journal = "A&A practice",
issn = "2325-7237",
publisher = "Lippincott Williams and Wilkins",
number = "9",

}

TY - JOUR

T1 - Two for One

T2 - A Case Report of Intravenous Lipid Emulsion to Treat Local Anesthetic Systemic Toxicity in Term Pregnancy

AU - Dun-Chi Lin, Jonathan

AU - Sivanesan, Eellan

AU - Horlocker, Terese T.

AU - Missair, Andres

PY - 2017/5/1

Y1 - 2017/5/1

N2 - Combined spinal-epidural (CSE) analgesia is a frequently used method of labor analgesia. Although it is considered safe and effective, CSE can be complicated by local anesthetic systemic toxicity (LAST), a potentially life-threatening condition. We present a case of LAST that developed in a primigravida 50 minutes after uneventful placement of a CSE. Her symptoms resolved within 10 minutes of administering intralipid emulsion. She subsequently underwent cesarean delivery under spinal anesthesia for failure to progress without sequelae in the mother or infant. LAST in pregnancy can occur at traditionally subthreshold dosing; anesthesiologists must be vigilant to ensure prompt and effective treatment.

AB - Combined spinal-epidural (CSE) analgesia is a frequently used method of labor analgesia. Although it is considered safe and effective, CSE can be complicated by local anesthetic systemic toxicity (LAST), a potentially life-threatening condition. We present a case of LAST that developed in a primigravida 50 minutes after uneventful placement of a CSE. Her symptoms resolved within 10 minutes of administering intralipid emulsion. She subsequently underwent cesarean delivery under spinal anesthesia for failure to progress without sequelae in the mother or infant. LAST in pregnancy can occur at traditionally subthreshold dosing; anesthesiologists must be vigilant to ensure prompt and effective treatment.

UR - http://www.scopus.com/inward/record.url?scp=85038261338&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85038261338&partnerID=8YFLogxK

U2 - 10.1213/XAA.0000000000000477

DO - 10.1213/XAA.0000000000000477

M3 - Article

VL - 8

SP - 235

EP - 237

JO - A&A practice

JF - A&A practice

SN - 2325-7237

IS - 9

ER -