Abstract
We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.
Original language | English (US) |
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Pages (from-to) | 279-281 |
Number of pages | 3 |
Journal | Journal of Maternal-Fetal and Neonatal Medicine |
Volume | 14 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2003 |
Keywords
- Karyotype
- Monochorionicity
- Twin-twin transfusion syndrome
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology