Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy

R. A. Quintero, O. T. Mueller, J. M. Martínez, J. Arroyo, E. Gilbert-Barness, D. Hilbelink, P. Papenhausen, M. Sutcliffe

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.

Original languageEnglish (US)
Pages (from-to)279-281
Number of pages3
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number4
StatePublished - Oct 2003


  • Karyotype
  • Monochorionicity
  • Twin-twin transfusion syndrome

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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