Twenty-third annual Pezcoller Symposium: Engineering Influences in Cancer Research

Peter Friedl, Jeff Hubbell, David Livingston, Enrico Mihich

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The cross-disciplinary focus of the meeting highlighted recent progress in physical and genetic analysis and engineering of cancer disease models. As the central theme, mechanical forces affecting cell signaling, growth, differentiation, and metastasis were discussed with emphasis on the tumor microenvironment and cellular immunity, taking into account novel nanotechnology, biosensing, and intravital microscopy tools to monitor animal cancer models and human cancer. Emerging themes were the role of extracellular matrix imposing mechanical mechanisms on tumor cell function, including microenvironmental cues controlling the movement of tumor and immune cells, advanced genetic animal models for cancer that better recapitulate human disease, and preclinical and clinical molecular imaging of tumor architecture and stiffness, as well as novel nanotechnologies for anticancer drug delivery.

Original languageEnglish (US)
Pages (from-to)841-844
Number of pages4
JournalCancer Research
Volume72
Issue number4
DOIs
StatePublished - Feb 15 2012

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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