Translated title of the contribution: Twenty nail dystrophy

Antonella Tosti, Federico Bardazzi, Bianca Maria Piraccini, Pier Alessandro Fanti

Research output: Contribution to journalShort surveypeer-review


Trachyonychia is a nail alteration which may be caused by several inflammatory diseases that affect the nail matrix keratinization. The pathogenesis of trachyonychia is still unknown but its occurrence in autoimmune or immune-mediated skin conditions suggests that an immunological reaction against nail matrix keratinocyte antigens may be involved. There are no clinical criteria which permit us to distinguish spongiotic trachyonychia, the most common type, from that due to other inflammatory skin diseases, i.e. lichen planus, psoriasis, eczema, pemphigus vulgaris. Spongiotic trachyonychia occurs in association with alopecia areata or as an idiopathic condition. Since spongiosis of the nail matrix is detected not only in trachyonychia, but also in the other nail abnormalities associated with alopecia areata, we can speculate that idiopathic spongiotic trachyonychia may represent a variety of alopecia areata limited to the nails.

Translated title of the contributionTwenty nail dystrophy
Original languageItalian
Pages (from-to)31-33
Number of pages3
JournalAnnali Italiani di Dermatologia Clinica e Sperimentale
Issue number1
StatePublished - Jan 1 1996
Externally publishedYes


  • alopecia areata
  • lichen planus
  • nail biopsy
  • trachyonychia
  • twenty nail dystrophy

ASJC Scopus subject areas

  • Dermatology


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