Abstract
After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about 5 days. The possible significance of this result is discussed with regard to control of protein synthesis.
| Original language | English |
|---|---|
| Pages (from-to) | 1093-1095 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 149 |
| Issue number | 3688 |
| State | Published - Dec 1 1965 |
| Externally published | Yes |
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Cite this
Turnover of ribosomal RNA in rat liver. / Loeb, John N.; Howell, R.; Tomkins, Gordon M.
In: Science, Vol. 149, No. 3688, 01.12.1965, p. 1093-1095.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Turnover of ribosomal RNA in rat liver
AU - Loeb, John N.
AU - Howell, R.
AU - Tomkins, Gordon M.
PY - 1965/12/1
Y1 - 1965/12/1
N2 - After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about 5 days. The possible significance of this result is discussed with regard to control of protein synthesis.
AB - After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about 5 days. The possible significance of this result is discussed with regard to control of protein synthesis.
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UR - http://www.scopus.com/inward/citedby.url?scp=37049243465&partnerID=8YFLogxK
M3 - Article
C2 - 5826520
AN - SCOPUS:37049243465
VL - 149
SP - 1093
EP - 1095
JO - Science
JF - Science
SN - 0036-8075
IS - 3688
ER -