Abstract
After a single injection of radioactive orotic acid and a "chase" of nonradioactive precursor, the specific activity of ribosomal RNA in rat liver decreases logarithmically at a rate corresponding to a half-life of about 5 days. The possible significance of this result is discussed with regard to control of protein synthesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1093-1095 |
| Number of pages | 3 |
| Journal | Science |
| Volume | 149 |
| Issue number | 3688 |
| DOIs | |
| State | Published - Jan 1 1965 |
| Externally published | Yes |
ASJC Scopus subject areas
- General
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Cite this
Loeb, J. N., Rodney Howell, R., & Tomkins, G. M. (1965). Turnover of ribosomal RNA in rat liver. Science, 149(3688), 1093-1095. https://doi.org/10.1126/science.149.3688.1093