Trophoblastic pseudotumor-Evidence of malignant disease potential

Leo B. Twiggs, Takashi Okagaki, George L. Phillips, John R. Stroemer, Leon L. Adcock

Research output: Contribution to journalArticle

87 Citations (Scopus)

Abstract

Trophoblastic pseudotumor, the histopathologic entity described by Kurman and associates (R. J. Kurman, R. E. Scully, and H. J. Norris, Cancer 38, 1214-1226 (1976)), has been considered in the scheme of gestational trophoblastic neoplasia as an exaggerated form of syncytial endometritis and, therefore, associated with a benign outcome. The manifestation of malignant sequalae and ultimate demise of a patient in a recognized case of trophoblastic pseudotumor is presented. Light and electron microscopic studies and autopsy findings are discussed. Therapies, both surgical and chemotherapeutic, and serum assay of the β subunit of human chorionic gonadotropin are correlated to the clinical course.

Original languageEnglish
Pages (from-to)238-248
Number of pages11
JournalGynecologic Oncology
Volume12
Issue number2
DOIs
StatePublished - Jan 1 1981
Externally publishedYes

Fingerprint

Gestational Trophoblastic Disease
Endometritis
Chorionic Gonadotropin
Autopsy
Electrons
Light
Serum
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Twiggs, L. B., Okagaki, T., Phillips, G. L., Stroemer, J. R., & Adcock, L. L. (1981). Trophoblastic pseudotumor-Evidence of malignant disease potential. Gynecologic Oncology, 12(2), 238-248. https://doi.org/10.1016/0090-8258(81)90153-0

Trophoblastic pseudotumor-Evidence of malignant disease potential. / Twiggs, Leo B.; Okagaki, Takashi; Phillips, George L.; Stroemer, John R.; Adcock, Leon L.

In: Gynecologic Oncology, Vol. 12, No. 2, 01.01.1981, p. 238-248.

Research output: Contribution to journalArticle

Twiggs, LB, Okagaki, T, Phillips, GL, Stroemer, JR & Adcock, LL 1981, 'Trophoblastic pseudotumor-Evidence of malignant disease potential', Gynecologic Oncology, vol. 12, no. 2, pp. 238-248. https://doi.org/10.1016/0090-8258(81)90153-0
Twiggs LB, Okagaki T, Phillips GL, Stroemer JR, Adcock LL. Trophoblastic pseudotumor-Evidence of malignant disease potential. Gynecologic Oncology. 1981 Jan 1;12(2):238-248. https://doi.org/10.1016/0090-8258(81)90153-0
Twiggs, Leo B. ; Okagaki, Takashi ; Phillips, George L. ; Stroemer, John R. ; Adcock, Leon L. / Trophoblastic pseudotumor-Evidence of malignant disease potential. In: Gynecologic Oncology. 1981 ; Vol. 12, No. 2. pp. 238-248.
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