Abstract
Background Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Anti-proliferative drug-eluting stents are an alternative for reducing in-stent stenosis at the vertebral artery origin. Methods This retrospective study included five consecutive patients treated with anti-proliferative drug-eluting stents. The patients' demographics, indications for treatment, procedural technique, and clinical and radiographic follow-up are presented along with a review of the literature. Results No peri-procedural complications occurred. One patient had a transient ischemic attack (TIA) during the follow-up period. No patients had hemodynamically significant (>50%) in-stent stenosis at follow-up. Among the 287 cases reported in the literature, there were two strokes (.7%), four TIAs (1.4%), and no procedurally related deaths. Among patients undergoing angiographic follow-up, 26% were found to have >50% in-stent stenosis. Conclusions Anti-proliferative drug-eluting stents hold promise for reducing in-stent stenosis at the vertebral artery origin.
| Original language | English |
|---|---|
| Pages (from-to) | 175-179 |
| Number of pages | 5 |
| Journal | Journal of Neuroimaging |
| Volume | 20 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2010 |
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Keywords
- Drug-eluting
- Stenosis
- Stent
- Stroke
- Vertebral artery origin
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
Cite this
Treatment of vertebral artery origin stenosis with anti-proliferative drug-eluting stents : Neurointerventional report. / Edgell, Randall C.; Yavagal, Dileep R; Drazin, Doniel; Olivera, Raul; Boulos, Alan S.
In: Journal of Neuroimaging, Vol. 20, No. 2, 01.04.2010, p. 175-179.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Treatment of vertebral artery origin stenosis with anti-proliferative drug-eluting stents
T2 - Neurointerventional report
AU - Edgell, Randall C.
AU - Yavagal, Dileep R
AU - Drazin, Doniel
AU - Olivera, Raul
AU - Boulos, Alan S.
PY - 2010/4/1
Y1 - 2010/4/1
N2 - Background Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Anti-proliferative drug-eluting stents are an alternative for reducing in-stent stenosis at the vertebral artery origin. Methods This retrospective study included five consecutive patients treated with anti-proliferative drug-eluting stents. The patients' demographics, indications for treatment, procedural technique, and clinical and radiographic follow-up are presented along with a review of the literature. Results No peri-procedural complications occurred. One patient had a transient ischemic attack (TIA) during the follow-up period. No patients had hemodynamically significant (>50%) in-stent stenosis at follow-up. Among the 287 cases reported in the literature, there were two strokes (.7%), four TIAs (1.4%), and no procedurally related deaths. Among patients undergoing angiographic follow-up, 26% were found to have >50% in-stent stenosis. Conclusions Anti-proliferative drug-eluting stents hold promise for reducing in-stent stenosis at the vertebral artery origin.
AB - Background Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Anti-proliferative drug-eluting stents are an alternative for reducing in-stent stenosis at the vertebral artery origin. Methods This retrospective study included five consecutive patients treated with anti-proliferative drug-eluting stents. The patients' demographics, indications for treatment, procedural technique, and clinical and radiographic follow-up are presented along with a review of the literature. Results No peri-procedural complications occurred. One patient had a transient ischemic attack (TIA) during the follow-up period. No patients had hemodynamically significant (>50%) in-stent stenosis at follow-up. Among the 287 cases reported in the literature, there were two strokes (.7%), four TIAs (1.4%), and no procedurally related deaths. Among patients undergoing angiographic follow-up, 26% were found to have >50% in-stent stenosis. Conclusions Anti-proliferative drug-eluting stents hold promise for reducing in-stent stenosis at the vertebral artery origin.
KW - Drug-eluting
KW - Stenosis
KW - Stent
KW - Stroke
KW - Vertebral artery origin
UR - http://www.scopus.com/inward/record.url?scp=77950619539&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950619539&partnerID=8YFLogxK
U2 - 10.1111/j.1552-6569.2008.00330.x
DO - 10.1111/j.1552-6569.2008.00330.x
M3 - Article
C2 - 19040627
AN - SCOPUS:77950619539
VL - 20
SP - 175
EP - 179
JO - Journal of Neuroimaging
JF - Journal of Neuroimaging
SN - 1051-2284
IS - 2
ER -