Abstract
Background Vertebral artery origin stenosis is a known cause of stroke that is treatable with angioplasty and stenting. Previous studies have demonstrated that this technique is safe but is limited by high rates of in-stent stenosis. Anti-proliferative drug-eluting stents are an alternative for reducing in-stent stenosis at the vertebral artery origin. Methods This retrospective study included five consecutive patients treated with anti-proliferative drug-eluting stents. The patients' demographics, indications for treatment, procedural technique, and clinical and radiographic follow-up are presented along with a review of the literature. Results No peri-procedural complications occurred. One patient had a transient ischemic attack (TIA) during the follow-up period. No patients had hemodynamically significant (>50%) in-stent stenosis at follow-up. Among the 287 cases reported in the literature, there were two strokes (.7%), four TIAs (1.4%), and no procedurally related deaths. Among patients undergoing angiographic follow-up, 26% were found to have >50% in-stent stenosis. Conclusions Anti-proliferative drug-eluting stents hold promise for reducing in-stent stenosis at the vertebral artery origin.
Original language | English (US) |
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Pages (from-to) | 175-179 |
Number of pages | 5 |
Journal | Journal of Neuroimaging |
Volume | 20 |
Issue number | 2 |
DOIs | |
State | Published - Apr 2010 |
Keywords
- Drug-eluting
- Stenosis
- Stent
- Stroke
- Vertebral artery origin
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology