Treatment of Strongyloides stercoralis hyperinfection-associated septic shock and acute respiratory distress syndrome with drotrecogin alfa (activated) in a renal transplant recipient

J. M. Huston, S. R. Eachempati, J. R. Rodney, C. Cayci, D. Fusco, M. Mathew, J. Shou, M. J. Goldstein, S. Kapur, P. S. Barie

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We report a case of Strongyloides stercoralis hyperinfection syndrome in a renal transplant recipient complicated by septic shock, acute respiratory distress syndrome, and Klebsiella pneumoniae superinfection. The patient was treated successfully with drotrecogin alfa (activated), parenteral ivermectin, albendazole, and piperacillin/tazobactam. This outcome suggests that drotrecogin alfa (activated) may be useful therapy for transplant recipients who develop severe sepsis or septic shock secondary to potentially lethal opportunistic infections.

Original languageEnglish (US)
Pages (from-to)277-280
Number of pages4
JournalTransplant Infectious Disease
Volume11
Issue number3
DOIs
StatePublished - Jun 1 2009

Keywords

  • Drotrecogin alfa (activated)
  • Ivermectin
  • Renal transplantation
  • Severe sepsis
  • Strongyloides stercoralis

ASJC Scopus subject areas

  • Infectious Diseases
  • Transplantation

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