Treatment of Primary Writing Tremor with Botulinum Toxin Type a Injections: Report of a Case Series

Spiridon Papapetropoulos, Carlos Singer

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Primary writing tremor is a rare motor disorder in which tremor occurs primarily during writing and is not accompanied by other neurological symptoms and/or signs. Its etiopathogenesis is unknown, and treatment approaches remain largely empirical. Based on the effectiveness of botulinum toxin injections in writing dysfunction, we effectively used botulinum toxin type A for the treatment of primary writing tremor in a series of patients seen over a period of 5 years. Of the 5 patients, four received injections and reported significant and sustained treatment benefit for a period of at least 1 year. One patient declined botulinum toxin injections and responded moderately when treated with trihexyphenidyl.

Original languageEnglish (US)
Pages (from-to)364-367
Number of pages4
JournalClinical neuropharmacology
Volume29
Issue number6
DOIs
StatePublished - Nov 1 2006

Keywords

  • Botulinum toxin type A
  • Case series
  • Clinical characteristics
  • Dystonia
  • Primary writing tremor
  • Treatment

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Clinical Neurology
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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