Treatment of onychomycosis with oral antifungal agents

Matilde Iorizzo, Bianca Maria Piraccini, Giulia Rech, Antonella Tosti

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Onychomycosis is the most common nail disease and describes the invasion of the nail by fungi. Different clinical patterns of infection depend on the way and the extent by which fungi colonise the nail: distal subungual onychomycosis, proximal subungual onychomycosis, white superficial onychomycosis, endonyx onychomycosis and total dystropic onychomycosis. The type of nail invasion depends on both the fungus responsible and on host susceptibility. Treatment of onychomycosis depends on the clinical type of the onychomycosis, the number of affected nails and the severity of nail involvement. The goals for antifungal therapy are mycological cure and a normal looking nail. In this paper the treatment of onychomycosis with oral antifungal agents will be reviewed.

Original languageEnglish (US)
Pages (from-to)435-440
Number of pages6
JournalExpert Opinion on Drug Delivery
Issue number3
StatePublished - May 1 2005
Externally publishedYes


  • Nail
  • Onychomycosis
  • Oral antifungal
  • Therapy

ASJC Scopus subject areas

  • Pharmaceutical Science


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