Treatment of mood disorders

Charles B. Nemeroff, Michael J. Owens

Research output: Contribution to journalArticle

203 Scopus citations

Abstract

Depression is a leading cause of morbidity and mortality, and its treatment includes a high percentage of the medications prescribed by physicians. Available antidepressant drugs are safe and effective, but less than half of all patients attain complete remission after therapy with a single anti-depressant. Others exhibit partial, refractory or intolerant responses to treatment, emphasizing the need to discover new antidepressants. The mechanisms of action of available medications are directing the field toward new research avenues. This review highlights those areas we believe will influence the field and soon lead to better treatment.

Original languageEnglish (US)
Pages (from-to)1068-1070
Number of pages3
JournalNature Neuroscience
Volume5
Issue number11s
DOIs
StatePublished - Nov 2002
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Treatment of mood disorders'. Together they form a unique fingerprint.

  • Cite this