Treatment of mood disorders

Charles Nemeroff, Michael J. Owens

Research output: Contribution to journalArticle

195 Citations (Scopus)

Abstract

Depression is a leading cause of morbidity and mortality, and its treatment includes a high percentage of the medications prescribed by physicians. Available antidepressant drugs are safe and effective, but less than half of all patients attain complete remission after therapy with a single anti-depressant. Others exhibit partial, refractory or intolerant responses to treatment, emphasizing the need to discover new antidepressants. The mechanisms of action of available medications are directing the field toward new research avenues. This review highlights those areas we believe will influence the field and soon lead to better treatment.

Original languageEnglish
Pages (from-to)1068-1070
Number of pages3
JournalNature Neuroscience
Volume5
Issue numberSUPPL.
DOIs
StatePublished - Nov 1 2002
Externally publishedYes

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Mood Disorders
Antidepressive Agents
Therapeutics
Depression
Morbidity
Physicians
Mortality
Research

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Treatment of mood disorders. / Nemeroff, Charles; Owens, Michael J.

In: Nature Neuroscience, Vol. 5, No. SUPPL., 01.11.2002, p. 1068-1070.

Research output: Contribution to journalArticle

Nemeroff, C & Owens, MJ 2002, 'Treatment of mood disorders', Nature Neuroscience, vol. 5, no. SUPPL., pp. 1068-1070. https://doi.org/10.1038/nn943
Nemeroff, Charles ; Owens, Michael J. / Treatment of mood disorders. In: Nature Neuroscience. 2002 ; Vol. 5, No. SUPPL. pp. 1068-1070.
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