Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.
|Original language||English (US)|
|Journal||Journal of Investigative Dermatology Symposium Proceedings|
|State||Published - Jan 2018|
ASJC Scopus subject areas
- Molecular Biology
- Cell Biology