Treatment of Alopecia Areata with Simvastatin/Ezetimibe

Jessica Cervantes, Joaquin J Jimenez, Gina M. DelCanto, Antonella Tosti

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Alopecia areata (AA) is an autoimmune disorder characterized by T lymphocytic infiltrates around the bulbar region of hair follicles. Statins have surfaced as potential therapeutic agents for AA, partly because of their modulation of the JAK/STAT pathway. Some data indicate that statins are a possible option for acute, but not chronic, longstanding AA. Animal studies suggest that treatment with statins increases CD4+/CD25+/Foxp3+ populations in AA-affected mice.

Original languageEnglish (US)
Pages (from-to)S25-S31
JournalJournal of Investigative Dermatology Symposium Proceedings
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2018

Fingerprint

Alopecia Areata
Simvastatin
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hair Follicle
Ezetimibe
Population

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

Treatment of Alopecia Areata with Simvastatin/Ezetimibe. / Cervantes, Jessica; Jimenez, Joaquin J; DelCanto, Gina M.; Tosti, Antonella.

In: Journal of Investigative Dermatology Symposium Proceedings, Vol. 19, No. 1, 01.01.2018, p. S25-S31.

Research output: Contribution to journalReview article

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