Treatment by assisted conception of severe male factor infertility due to spinal cord injury or other neurologic impairment

Nancy L. Brackett, Mick Abae, Osvaldo F. Padron, Charles M. Lynne

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Purpose: This retrospective study evaluated the pregnancy rates of 23 couples with male factor infertility due to traumatic spinal cord injury (N = 21), multiple sclerosis (N = 1) or transverse myelitis (N = 1). Methods: Ovulation induction by clomiphene citrate or gonadotropins was used in combination with intrauterine insemination as an initial approach for assisted conception in all but one couple. Results: Six pregnancies occurred in 60 cycles of intrauterine insemination (mean of 2.6 cycles). In this group, the cumulative pregnancy rate was 26%. Six couples who failed after a total of 33 intrauterine insemination cycles (mean of 5.5 cycles), and 1 couple with no previous intrauterine insemination cycles, initiated 10 cycles of in vitro fertilization (mean of 1.4 cycles). In this group, five pregnancies occurred. The pregnancy rate was 71%. Conclusion: We conclude that ovulation induction in combination with intrauterine insemination offers an effective initial therapy of severe male factor infertility due to spinal cord injury.

Original languageEnglish (US)
Pages (from-to)210-216
Number of pages7
JournalJournal of Assisted Reproduction and Genetics
Volume12
Issue number3
DOIs
StatePublished - Mar 1 1995

Keywords

  • electroejaculation
  • GIFT
  • IUI
  • IVF
  • spinal cord injury

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology
  • Genetics
  • Developmental Biology

Fingerprint Dive into the research topics of 'Treatment by assisted conception of severe male factor infertility due to spinal cord injury or other neurologic impairment'. Together they form a unique fingerprint.

Cite this