Transport of Multi-Electrolytes in Charged Hydrated Biological Soft Tissues

Weiyong Gu, W. M. Lai, V. C. Mow

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

A mechano-electrochemical theory for charged hydrated soft tissues with multielectrolytes was developed based on the continuum mixture theory. The momentum equations for water and ions were derived in terms of a mechanochemical force (gradient of water chemical potential), electrochemical forces (gradient of Nernst potentials) and an electrical force (gradient of electrical potential). The theory was shown tobe consistent with all existing specialized theories. Using this theory, some mechano-electrokinetic properties of charged isotropic tissues were studied. The well-known Hodgkin-Huxley equation for resting cell membrane potential was derived and the phenomenon of electro-osmotic flow in charged hydrated soft tissues was investigated. Analyses show that the tissue fixed charge density plays an important role in controlling the transport of water and ions in charged hydrated soft tissues.

Original languageEnglish
Pages (from-to)143-157
Number of pages15
JournalTransport in Porous Media
Volume34
Issue number1-3
StatePublished - Mar 1 1999

Fingerprint

Electrolytes
Tissue
Water
Ions
Chemical potential
Cell membranes
Charge density
Momentum

Keywords

  • Charged hydrated soft tissues
  • Electro-osmosis
  • Mixture theory
  • Transport

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Catalysis

Cite this

Transport of Multi-Electrolytes in Charged Hydrated Biological Soft Tissues. / Gu, Weiyong; Lai, W. M.; Mow, V. C.

In: Transport in Porous Media, Vol. 34, No. 1-3, 01.03.1999, p. 143-157.

Research output: Contribution to journalArticle

Gu, Weiyong ; Lai, W. M. ; Mow, V. C. / Transport of Multi-Electrolytes in Charged Hydrated Biological Soft Tissues. In: Transport in Porous Media. 1999 ; Vol. 34, No. 1-3. pp. 143-157.
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