Transport of Multi-Electrolytes in Charged Hydrated Biological Soft Tissues

W. Y. Gu, W. M. Lai, V. C. Mow

Research output: Contribution to journalConference articlepeer-review

74 Scopus citations


A mechano-electrochemical theory for charged hydrated soft tissues with multielectrolytes was developed based on the continuum mixture theory. The momentum equations for water and ions were derived in terms of a mechanochemical force (gradient of water chemical potential), electrochemical forces (gradient of Nernst potentials) and an electrical force (gradient of electrical potential). The theory was shown tobe consistent with all existing specialized theories. Using this theory, some mechano-electrokinetic properties of charged isotropic tissues were studied. The well-known Hodgkin-Huxley equation for resting cell membrane potential was derived and the phenomenon of electro-osmotic flow in charged hydrated soft tissues was investigated. Analyses show that the tissue fixed charge density plays an important role in controlling the transport of water and ions in charged hydrated soft tissues.

Original languageEnglish (US)
Pages (from-to)143-157
Number of pages15
JournalTransport in Porous Media
Issue number1-3
StatePublished - Mar 1999
EventProceedings of the 1997 EUROMECH Colloquium 366, 'Porous Media - Theory and Experiments' - Essen, Germany
Duration: Jun 23 1997Jun 27 1997


  • Charged hydrated soft tissues
  • Electro-osmosis
  • Mixture theory
  • Transport

ASJC Scopus subject areas

  • Chemical Engineering(all)
  • Catalysis


Dive into the research topics of 'Transport of Multi-Electrolytes in Charged Hydrated Biological Soft Tissues'. Together they form a unique fingerprint.

Cite this