Transplantation for the treatment of intra-abdominal fibromatosis

P. Tryphonopoulos, D. Weppler, D. M. Levi, Seigo Nishida, J. R. Madariaga, T. Kato, N. Mittal, J. Moon, Gennaro Selvaggi, V. Esquenazi, G. Patricia Cantwell, Phillip Ruiz, J. Miller, A. G. Tzakis

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Materials and methods. During the last 9 years we treated 14 patients with a diagnosis of intra-abdominal fibromatosis. The 11 patients who received an intestinal allograft included isolated intestine (n = 6), liver-intestine (n = 1), intestine-kidney (n = 1), multivisceral (n = 1), multivisceral-kidney (n = 1), multivisceral-no liver (n = 1). Three patients received an intestinal autograft after partial abdominal evisceration and ex vivo tumor resection. Three patients additionally underwent an abdominal wall allograft. Results. At follow-up until August 2004, all autotransplant patients are alive. Four intestinal transplant patients died within the first postoperative month. There were three graft losses. A patient who lost his graft early postoperatively was retransplanted but died of sepsis shortly there after. Two more patients lost their graft due to severe rejection and were retransplanted successfully. Two patients developed desmoid tumor recurrence in their abdominal or thoracic wall. Ten patients are alive 1 to 9 years posttransplantation. Nine have fully functioning grafts and one patient requires TPN supplementation at night due to dysmotility of her autograft. Conclusion. Intestinal allo-, or autotransplantation combined with transplantation of the abdominal wall can be lifesaving for patients suffering from extensive intra-abdominal fibromatosis.

Original languageEnglish
Pages (from-to)1379-1380
Number of pages2
JournalTransplantation Proceedings
Volume37
Issue number2
DOIs
StatePublished - Mar 1 2005

Fingerprint

Abdominal Fibromatosis
Transplantation
Transplants
Autografts
Abdominal Wall
Therapeutics
Intestines
Allografts
Aggressive Fibromatosis
Kidney
Autologous Transplantation
Liver
Thoracic Wall

ASJC Scopus subject areas

  • Surgery
  • Transplantation

Cite this

Tryphonopoulos, P., Weppler, D., Levi, D. M., Nishida, S., Madariaga, J. R., Kato, T., ... Tzakis, A. G. (2005). Transplantation for the treatment of intra-abdominal fibromatosis. Transplantation Proceedings, 37(2), 1379-1380. https://doi.org/10.1016/j.transproceed.2004.12.218

Transplantation for the treatment of intra-abdominal fibromatosis. / Tryphonopoulos, P.; Weppler, D.; Levi, D. M.; Nishida, Seigo; Madariaga, J. R.; Kato, T.; Mittal, N.; Moon, J.; Selvaggi, Gennaro; Esquenazi, V.; Patricia Cantwell, G.; Ruiz, Phillip; Miller, J.; Tzakis, A. G.

In: Transplantation Proceedings, Vol. 37, No. 2, 01.03.2005, p. 1379-1380.

Research output: Contribution to journalArticle

Tryphonopoulos, P, Weppler, D, Levi, DM, Nishida, S, Madariaga, JR, Kato, T, Mittal, N, Moon, J, Selvaggi, G, Esquenazi, V, Patricia Cantwell, G, Ruiz, P, Miller, J & Tzakis, AG 2005, 'Transplantation for the treatment of intra-abdominal fibromatosis', Transplantation Proceedings, vol. 37, no. 2, pp. 1379-1380. https://doi.org/10.1016/j.transproceed.2004.12.218
Tryphonopoulos P, Weppler D, Levi DM, Nishida S, Madariaga JR, Kato T et al. Transplantation for the treatment of intra-abdominal fibromatosis. Transplantation Proceedings. 2005 Mar 1;37(2):1379-1380. https://doi.org/10.1016/j.transproceed.2004.12.218
Tryphonopoulos, P. ; Weppler, D. ; Levi, D. M. ; Nishida, Seigo ; Madariaga, J. R. ; Kato, T. ; Mittal, N. ; Moon, J. ; Selvaggi, Gennaro ; Esquenazi, V. ; Patricia Cantwell, G. ; Ruiz, Phillip ; Miller, J. ; Tzakis, A. G. / Transplantation for the treatment of intra-abdominal fibromatosis. In: Transplantation Proceedings. 2005 ; Vol. 37, No. 2. pp. 1379-1380.
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