Transperitoneal Laparoscopic Prostatectomy Does Not Increase Small Bowel Within the Target Volume for Postoperative Radiotherapy

Antonio Finelli, Sanoj Punnen, Tara Rosewall, Charles Catton, Neil Fleshner, Michael Jewett, John Trachtenberg, Cynthia Menard

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose: Laparoscopic or robot assisted laparoscopic radical prostatectomy is often performed via a transperitoneal approach for prostate cancer, in contrast to open retropubic radical prostatectomy. Theoretically transgressing the peritoneum may introduce small bowel loops into the pelvis, increasing the risk of small bowel injury with adjuvant radiotherapy. We compared the incidence of small bowel within the planning target volume for radiotherapy to the prostate bed in patients who underwent open retropubic and laparoscopic radical prostatectomy. Materials and Methods: A total of 25 patients recently treated with laparoscopic radical prostatectomy prospectively provided consent to undergo radiotherapy planning computerized tomography simulation to assess the incidence of small bowel within the prostate bed planning target volume. These studies were compared to radiotherapy planning computerized tomography in 50 patients who underwent open retropubic radical prostatectomy and received adjuvant or salvage radiotherapy for prostate cancer. For all computerized tomography images 1 blinded observer delineated the distal small bowel loops and 1 blinded radiation oncologist delineated the superior extent of clinical and planning target volumes. Results: The overlap rate between small bowel and planning target volume was 16% in the laparoscopic and open radical prostatectomy groups (p = 0.579). Conclusions: There is no difference between transperitoneal laparoscopic and open retropubic radical prostatectomy in the incidence of small bowel within the planning target volume for radiotherapy to the prostate bed. Thus, patients who undergo transperitoneal laparoscopic radical prostatectomy do not face a higher risk of toxicity or compromise due to adjuvant or salvage radiotherapy should they require it.

Original languageEnglish (US)
Pages (from-to)2280-2284
Number of pages5
JournalJournal of Urology
Volume182
Issue number5
DOIs
StatePublished - Nov 2009
Externally publishedYes

Fingerprint

Prostatectomy
Radiotherapy
Prostate
Tomography
Prostatic Neoplasms
Incidence
Adjuvant Radiotherapy
Peritoneum
Pelvis
Wounds and Injuries

Keywords

  • colon
  • laparoscopy
  • prostate
  • prostatectomy
  • radiotherapy

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

Cite this

Transperitoneal Laparoscopic Prostatectomy Does Not Increase Small Bowel Within the Target Volume for Postoperative Radiotherapy. / Finelli, Antonio; Punnen, Sanoj; Rosewall, Tara; Catton, Charles; Fleshner, Neil; Jewett, Michael; Trachtenberg, John; Menard, Cynthia.

In: Journal of Urology, Vol. 182, No. 5, 11.2009, p. 2280-2284.

Research output: Contribution to journalArticle

Finelli, Antonio ; Punnen, Sanoj ; Rosewall, Tara ; Catton, Charles ; Fleshner, Neil ; Jewett, Michael ; Trachtenberg, John ; Menard, Cynthia. / Transperitoneal Laparoscopic Prostatectomy Does Not Increase Small Bowel Within the Target Volume for Postoperative Radiotherapy. In: Journal of Urology. 2009 ; Vol. 182, No. 5. pp. 2280-2284.
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abstract = "Purpose: Laparoscopic or robot assisted laparoscopic radical prostatectomy is often performed via a transperitoneal approach for prostate cancer, in contrast to open retropubic radical prostatectomy. Theoretically transgressing the peritoneum may introduce small bowel loops into the pelvis, increasing the risk of small bowel injury with adjuvant radiotherapy. We compared the incidence of small bowel within the planning target volume for radiotherapy to the prostate bed in patients who underwent open retropubic and laparoscopic radical prostatectomy. Materials and Methods: A total of 25 patients recently treated with laparoscopic radical prostatectomy prospectively provided consent to undergo radiotherapy planning computerized tomography simulation to assess the incidence of small bowel within the prostate bed planning target volume. These studies were compared to radiotherapy planning computerized tomography in 50 patients who underwent open retropubic radical prostatectomy and received adjuvant or salvage radiotherapy for prostate cancer. For all computerized tomography images 1 blinded observer delineated the distal small bowel loops and 1 blinded radiation oncologist delineated the superior extent of clinical and planning target volumes. Results: The overlap rate between small bowel and planning target volume was 16{\%} in the laparoscopic and open radical prostatectomy groups (p = 0.579). Conclusions: There is no difference between transperitoneal laparoscopic and open retropubic radical prostatectomy in the incidence of small bowel within the planning target volume for radiotherapy to the prostate bed. Thus, patients who undergo transperitoneal laparoscopic radical prostatectomy do not face a higher risk of toxicity or compromise due to adjuvant or salvage radiotherapy should they require it.",
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