Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts

Yao-Shan Fan, Azra Raza, Joan Schumer, Sheila N. Jani Sait, AnneMarie W. Block, Michael Snyderman, Avery A. Sandberg

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.

Original languageEnglish
Pages (from-to)135-138
Number of pages4
JournalCancer Genetics and Cytogenetics
Volume29
Issue number1
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

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Refractory Anemia with Excess of Blasts
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Leukemia
Chromosome Aberrations
Blood Cells
Bone Marrow

ASJC Scopus subject areas

  • Cancer Research
  • Genetics
  • Molecular Biology

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Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts. / Fan, Yao-Shan; Raza, Azra; Schumer, Joan; Jani Sait, Sheila N.; Block, AnneMarie W.; Snyderman, Michael; Sandberg, Avery A.

In: Cancer Genetics and Cytogenetics, Vol. 29, No. 1, 01.01.1987, p. 135-138.

Research output: Contribution to journalArticle

Fan, Yao-Shan ; Raza, Azra ; Schumer, Joan ; Jani Sait, Sheila N. ; Block, AnneMarie W. ; Snyderman, Michael ; Sandberg, Avery A. / Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts. In: Cancer Genetics and Cytogenetics. 1987 ; Vol. 29, No. 1. pp. 135-138.
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