Abstract
A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 135-138 |
| Number of pages | 4 |
| Journal | Cancer Genetics and Cytogenetics |
| Volume | 29 |
| Issue number | 1 |
| DOIs | |
| State | Published - Nov 1987 |
| Externally published | Yes |
ASJC Scopus subject areas
- Molecular Biology
- Genetics
- Cancer Research
Fingerprint Dive into the research topics of 'Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts'. Together they form a unique fingerprint.
Cite this
Fan, Y. S., Raza, A., Schumer, J., Jani Sait, S. N., Block, A. M. W., Snyderman, M., & Sandberg, A. A. (1987). Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts. Cancer Genetics and Cytogenetics, 29(1), 135-138. https://doi.org/10.1016/0165-4608(87)90040-9