Abstract
A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
| Original language | English |
|---|---|
| Pages (from-to) | 135-138 |
| Number of pages | 4 |
| Journal | Cancer Genetics and Cytogenetics |
| Volume | 29 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1987 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Genetics
- Molecular Biology
Cite this
Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts. / Fan, Yao-Shan; Raza, Azra; Schumer, Joan; Jani Sait, Sheila N.; Block, AnneMarie W.; Snyderman, Michael; Sandberg, Avery A.
In: Cancer Genetics and Cytogenetics, Vol. 29, No. 1, 01.01.1987, p. 135-138.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts
AU - Fan, Yao-Shan
AU - Raza, Azra
AU - Schumer, Joan
AU - Jani Sait, Sheila N.
AU - Block, AnneMarie W.
AU - Snyderman, Michael
AU - Sandberg, Avery A.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
AB - A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
UR - http://www.scopus.com/inward/record.url?scp=0023199454&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023199454&partnerID=8YFLogxK
U2 - 10.1016/0165-4608(87)90040-9
DO - 10.1016/0165-4608(87)90040-9
M3 - Article
C2 - 3664444
AN - SCOPUS:0023199454
VL - 29
SP - 135
EP - 138
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1
ER -