TY - JOUR
T1 - Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts
AU - Fan, Yao Shan
AU - Raza, Azra
AU - Schumer, Joan
AU - Jani Sait, Sheila N.
AU - Block, Anne Marie W.
AU - Snyderman, Michael
AU - Sandberg, Avery A.
PY - 1987/11
Y1 - 1987/11
N2 - A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
AB - A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.
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U2 - 10.1016/0165-4608(87)90040-9
DO - 10.1016/0165-4608(87)90040-9
M3 - Article
C2 - 3664444
AN - SCOPUS:0023199454
VL - 29
SP - 135
EP - 138
JO - Cancer Genetics and Cytogenetics
JF - Cancer Genetics and Cytogenetics
SN - 0165-4608
IS - 1
ER -