Translocation t(6;9)(p22.3;q34) in myelodysplastic syndrome-Refractory anemia with excess blasts

Yao Shan Fan, Azra Raza, Joan Schumer, Sheila N. Jani Sait, Anne Marie W. Block, Michael Snyderman, Avery A. Sandberg

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


A 69-year-old male patient with refractory anemia with excess blasts (RAEB) was found to have a consistent chromosomal abnormality, t(6;9)(p22.3;q34), in the bone marrow and unstimulated peripheral blood cells. Twenty patients with t(6;9) and leukemia have been reported; some of them had a myelodysplastic syndrome (MDS) before developing overt ANLL. Our patient was still in the MDS stage when the t(6;9) was found. This result suggests that t(6;9) represents one of the pathways from MDS to leukemia in patients with ANLL.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalCancer Genetics and Cytogenetics
Issue number1
StatePublished - Nov 1987
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research


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