Transitions in the Prophylaxis, Treatment and Care of Patients with Venous Thromboembolism

Joshua D Lenchus

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Introduction: Patients experience numerous transitions, including changes in clinical status, pharmacologic treatment and prophylaxis, and progression through the physical locations of their healthcare setting as they advance through a venous thromboembolism (VTE) clinical experience. This review provides an overview of these transitions and highlights how they can impact clinical care. Methods: Major public resources (PubMed, MEDLINE, and Google Scholar) were searched using various combinations of the terms: “venous thromboembolism”, “deep vein thromboses”, “pulmonary embolism”, “transitions in care”, and “hospital protocols” to identify narrative reviews, professional guidelines, or primary manuscripts reporting protocol development strategies and/or clinical data, published in English from 2010 through January 2015. The studies included in this review were selected on the basis of extensive reading of the literature and the author’s clinical expertise. Results: VTE treatment and prophylaxis is a dynamic process requiring ongoing patient assessments and adjustments to therapeutic strategies as the patient progresses through various hospital and outpatient settings. Throughout these transitions in care, physicians need to be vigilant of any changes in the patient’s clinical condition which may impact the patient’s risk of VTE, and re-evaluate the intervention(s) employed when such changes occur. A standardized, interdisciplinary VTE clinical pathway developed for medical patients with acute VTE resulted in decreased utilization of hospital resources and healthcare costs, suggesting that further research is warranted in this area. Conclusion: The prevention and management of VTE can be optimized by the development and local implementation of standardized evidence-based clinical pathways.

Original languageEnglish (US)
Pages (from-to)29-45
Number of pages17
JournalAdvances in Therapy
Volume33
Issue number1
DOIs
StatePublished - Jan 1 2016

Fingerprint

Venous Thromboembolism
Patient Care
Critical Pathways
Therapeutics
Manuscripts
Hospital Costs
Pulmonary Embolism
PubMed
MEDLINE
Venous Thrombosis
Health Care Costs
Reading
Outpatients
Guidelines
Delivery of Health Care
Physicians
Research

Keywords

  • Clinical outcome
  • DOACs
  • Healthcare cost
  • NOACs
  • Pharmacologic treatment
  • Prophylaxis
  • Protocols
  • Transitions
  • Venous thromboembolism
  • VTE risk

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Medicine(all)

Cite this

Transitions in the Prophylaxis, Treatment and Care of Patients with Venous Thromboembolism. / Lenchus, Joshua D.

In: Advances in Therapy, Vol. 33, No. 1, 01.01.2016, p. 29-45.

Research output: Contribution to journalArticle

@article{54cdae2f8593436cadb08f4f027717c4,
title = "Transitions in the Prophylaxis, Treatment and Care of Patients with Venous Thromboembolism",
abstract = "Introduction: Patients experience numerous transitions, including changes in clinical status, pharmacologic treatment and prophylaxis, and progression through the physical locations of their healthcare setting as they advance through a venous thromboembolism (VTE) clinical experience. This review provides an overview of these transitions and highlights how they can impact clinical care. Methods: Major public resources (PubMed, MEDLINE, and Google Scholar) were searched using various combinations of the terms: “venous thromboembolism”, “deep vein thromboses”, “pulmonary embolism”, “transitions in care”, and “hospital protocols” to identify narrative reviews, professional guidelines, or primary manuscripts reporting protocol development strategies and/or clinical data, published in English from 2010 through January 2015. The studies included in this review were selected on the basis of extensive reading of the literature and the author’s clinical expertise. Results: VTE treatment and prophylaxis is a dynamic process requiring ongoing patient assessments and adjustments to therapeutic strategies as the patient progresses through various hospital and outpatient settings. Throughout these transitions in care, physicians need to be vigilant of any changes in the patient’s clinical condition which may impact the patient’s risk of VTE, and re-evaluate the intervention(s) employed when such changes occur. A standardized, interdisciplinary VTE clinical pathway developed for medical patients with acute VTE resulted in decreased utilization of hospital resources and healthcare costs, suggesting that further research is warranted in this area. Conclusion: The prevention and management of VTE can be optimized by the development and local implementation of standardized evidence-based clinical pathways.",
keywords = "Clinical outcome, DOACs, Healthcare cost, NOACs, Pharmacologic treatment, Prophylaxis, Protocols, Transitions, Venous thromboembolism, VTE risk",
author = "Lenchus, {Joshua D}",
year = "2016",
month = "1",
day = "1",
doi = "10.1007/s12325-015-0271-8",
language = "English (US)",
volume = "33",
pages = "29--45",
journal = "Advances in Therapy",
issn = "0741-238X",
publisher = "Health Communications Inc.",
number = "1",

}

TY - JOUR

T1 - Transitions in the Prophylaxis, Treatment and Care of Patients with Venous Thromboembolism

AU - Lenchus, Joshua D

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Introduction: Patients experience numerous transitions, including changes in clinical status, pharmacologic treatment and prophylaxis, and progression through the physical locations of their healthcare setting as they advance through a venous thromboembolism (VTE) clinical experience. This review provides an overview of these transitions and highlights how they can impact clinical care. Methods: Major public resources (PubMed, MEDLINE, and Google Scholar) were searched using various combinations of the terms: “venous thromboembolism”, “deep vein thromboses”, “pulmonary embolism”, “transitions in care”, and “hospital protocols” to identify narrative reviews, professional guidelines, or primary manuscripts reporting protocol development strategies and/or clinical data, published in English from 2010 through January 2015. The studies included in this review were selected on the basis of extensive reading of the literature and the author’s clinical expertise. Results: VTE treatment and prophylaxis is a dynamic process requiring ongoing patient assessments and adjustments to therapeutic strategies as the patient progresses through various hospital and outpatient settings. Throughout these transitions in care, physicians need to be vigilant of any changes in the patient’s clinical condition which may impact the patient’s risk of VTE, and re-evaluate the intervention(s) employed when such changes occur. A standardized, interdisciplinary VTE clinical pathway developed for medical patients with acute VTE resulted in decreased utilization of hospital resources and healthcare costs, suggesting that further research is warranted in this area. Conclusion: The prevention and management of VTE can be optimized by the development and local implementation of standardized evidence-based clinical pathways.

AB - Introduction: Patients experience numerous transitions, including changes in clinical status, pharmacologic treatment and prophylaxis, and progression through the physical locations of their healthcare setting as they advance through a venous thromboembolism (VTE) clinical experience. This review provides an overview of these transitions and highlights how they can impact clinical care. Methods: Major public resources (PubMed, MEDLINE, and Google Scholar) were searched using various combinations of the terms: “venous thromboembolism”, “deep vein thromboses”, “pulmonary embolism”, “transitions in care”, and “hospital protocols” to identify narrative reviews, professional guidelines, or primary manuscripts reporting protocol development strategies and/or clinical data, published in English from 2010 through January 2015. The studies included in this review were selected on the basis of extensive reading of the literature and the author’s clinical expertise. Results: VTE treatment and prophylaxis is a dynamic process requiring ongoing patient assessments and adjustments to therapeutic strategies as the patient progresses through various hospital and outpatient settings. Throughout these transitions in care, physicians need to be vigilant of any changes in the patient’s clinical condition which may impact the patient’s risk of VTE, and re-evaluate the intervention(s) employed when such changes occur. A standardized, interdisciplinary VTE clinical pathway developed for medical patients with acute VTE resulted in decreased utilization of hospital resources and healthcare costs, suggesting that further research is warranted in this area. Conclusion: The prevention and management of VTE can be optimized by the development and local implementation of standardized evidence-based clinical pathways.

KW - Clinical outcome

KW - DOACs

KW - Healthcare cost

KW - NOACs

KW - Pharmacologic treatment

KW - Prophylaxis

KW - Protocols

KW - Transitions

KW - Venous thromboembolism

KW - VTE risk

UR - http://www.scopus.com/inward/record.url?scp=84957441885&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84957441885&partnerID=8YFLogxK

U2 - 10.1007/s12325-015-0271-8

DO - 10.1007/s12325-015-0271-8

M3 - Article

VL - 33

SP - 29

EP - 45

JO - Advances in Therapy

JF - Advances in Therapy

SN - 0741-238X

IS - 1

ER -