Abstract
Technologies for controlling mosquito vectors based on genetic manipulation and the release of genetically modified mosquitoes (GMMs) are gaining ground. However, concrete epidemiological evidence of their effectiveness, sustainability, and impact on the environment and nontarget species is lacking; no reliable ecological evidence on the potential interactions among GMMs, target populations, and other mosquito species populations exists; and no GMM technology has yet been approved by the WHO Vector Control Advisory Group. Our opinion is that, although GMMs may be considered a promising control tool, more studies are needed to assess their true effectiveness, risks, and benefits. Overall, several lines of evidence must be provided before GMM-based control strategies can be used under the integrated vector management framework.
| Original language | English (US) |
|---|---|
| Journal | Trends in Parasitology |
| DOIs | |
| State | Accepted/In press - Jan 1 2018 |
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Keywords
- genetically modified mosquitoes
- integrated vector management
- mosquito vectors
- vector-borne diseases
ASJC Scopus subject areas
- Parasitology
- Infectious Diseases
Cite this
Transgenic Mosquitoes – Fact or Fiction? / Wilke, André B.B.; Beier, John C; Benelli, Giovanni.
In: Trends in Parasitology, 01.01.2018.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Transgenic Mosquitoes – Fact or Fiction?
AU - Wilke, André B.B.
AU - Beier, John C
AU - Benelli, Giovanni
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Technologies for controlling mosquito vectors based on genetic manipulation and the release of genetically modified mosquitoes (GMMs) are gaining ground. However, concrete epidemiological evidence of their effectiveness, sustainability, and impact on the environment and nontarget species is lacking; no reliable ecological evidence on the potential interactions among GMMs, target populations, and other mosquito species populations exists; and no GMM technology has yet been approved by the WHO Vector Control Advisory Group. Our opinion is that, although GMMs may be considered a promising control tool, more studies are needed to assess their true effectiveness, risks, and benefits. Overall, several lines of evidence must be provided before GMM-based control strategies can be used under the integrated vector management framework.
AB - Technologies for controlling mosquito vectors based on genetic manipulation and the release of genetically modified mosquitoes (GMMs) are gaining ground. However, concrete epidemiological evidence of their effectiveness, sustainability, and impact on the environment and nontarget species is lacking; no reliable ecological evidence on the potential interactions among GMMs, target populations, and other mosquito species populations exists; and no GMM technology has yet been approved by the WHO Vector Control Advisory Group. Our opinion is that, although GMMs may be considered a promising control tool, more studies are needed to assess their true effectiveness, risks, and benefits. Overall, several lines of evidence must be provided before GMM-based control strategies can be used under the integrated vector management framework.
KW - genetically modified mosquitoes
KW - integrated vector management
KW - mosquito vectors
KW - vector-borne diseases
UR - http://www.scopus.com/inward/record.url?scp=85042905789&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042905789&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2018.02.003
DO - 10.1016/j.pt.2018.02.003
M3 - Article
C2 - 29526402
AN - SCOPUS:85042905789
JO - Trends in Parasitology
JF - Trends in Parasitology
SN - 1471-4922
ER -