Transfer RNA nucleotidyltransferase repairs all transfer RNAs randomly

Murray P. Deutscher, Jeffrey A. Evans

Research output: Contribution to journalLetterpeer-review

17 Scopus citations


Total Escherichia coli transfer RNA was converted to tRNA-C-C by periodate oxidation and partially repaired with either E. coli or rabbit liver tRNA nucleotidyltransferase. Aminoacylation of the partially repaired molecules indicated that individual tRNA species were each repaired to the same extent as the total population of molecules. These results support a non-specific, scavenger role for tRNA nucleotidyltransferase.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalJournal of molecular biology
Issue number4
StatePublished - Feb 5 1977

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology


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