Transcranial Doppler assessment performed at rest and during mental activities in patients with postconcussion syndrome

S. P. Sarkanji, V. Demarin, T. Rundek, I. Martinic

Research output: Contribution to journalArticle

Abstract

The purpose of the study was to detect selective circulatory changes during cognitive activities in patients suffering from postconcussional syndrome. The blood flow velocity was measured in both middle cerebral arteries in 15 patients by transcranial Doppler sonography during rest and while performing cognitive tasks, alternately. Fifteen healthy volunteers of matched age served as controls. Blood flow velocity values in the left and right middle cerebral arteries during rest and during cognitive activation phases (for all tasks) were significantly lower in the patients than in the control group. The time course of blood flow velocity during cognitive activation showed an initial increase to maximum and then a decrease in velocity. The increase was lower in the patients than in the control group. There was a longer adaptation phase to the steady state period in the patients than in the control group. The results suggest that vasomotor reactivity is disturbed in patients suffering from postconcussional syndrome.

Original languageEnglish (US)
Pages (from-to)423-428
Number of pages6
JournalPeriodicum Biologorum
Volume95
Issue number4
StatePublished - Dec 1 1993

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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