Towards defining receptors for l-tyrosine and l-DOPA

Andrzej Slominski; Ralf Paus

doi:10.1016/0303-7207(94)90001-9

Towards defining receptors for l-tyrosine and l-DOPA

Andrzej Slominski, Ralf Paus

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

We postulate that in mammalian systems neurotransmitter and hormone-like functions of l-tyrosine (LT) and l-DOPA (LD) are mediated via specific membrane-bound and/or nuclear receptors. The structure and function of these receptors may represent an evolutionary continuum of regulatory proteins binding LT or LD in unicellular and lower multicellular organisms.

Original language	English (US)
Pages (from-to)	C7-C11
Journal	Molecular and Cellular Endocrinology
Volume	99
Issue number	2
DOIs	https://doi.org/10.1016/0303-7207(94)90001-9
State	Published - Mar 1994
Externally published	Yes

Keywords

Melanocyte
Receptor
Receptor evolution
l-DOPA
l-Tyrosine

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology

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10.1016/0303-7207(94)90001-9

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abstract = "We postulate that in mammalian systems neurotransmitter and hormone-like functions of l-tyrosine (LT) and l-DOPA (LD) are mediated via specific membrane-bound and/or nuclear receptors. The structure and function of these receptors may represent an evolutionary continuum of regulatory proteins binding LT or LD in unicellular and lower multicellular organisms.",

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KW - Receptor evolution

KW - l-DOPA

KW - l-Tyrosine

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