Toward a population genetic framework of developmental evolution

The costs, limits, and consequences of phenotypic plasticity

Emilie C. Snell-Rood, James Van Dyken, Tami Cruickshank, Michael J. Wade, Armin P. Moczek

Research output: Contribution to journalArticle

158 Citations (Scopus)

Abstract

Adaptive phenotypic plasticity allows organisms to cope with environmental variability, and yet, despite its adaptive significance, phenotypic plasticity is neither ubiquitous nor infinite. In this review, we merge developmental and population genetic perspectives to explore costs and limits on the evolution of plasticity. Specifically, we focus on the role of modularity in developmental genetic networks as a mechanism underlying phenotypic plasticity, and apply to it lessons learned from population genetic theory on the interplay between relaxed selection and mutation accumulation. We argue that the environmental specificity of gene expression and the associated reduction in pleiotropic constraints drive a fundamental tradeoff between the range of plasticity that can be accommodated and mutation accumulation in alternative developmental networks. This tradeoff has broad implications for understanding the origin and maintenance of plasticity and may contribute to a better understanding of the role of plasticity in the origin, diversification, and loss of phenotypic diversity.

Original languageEnglish (US)
Pages (from-to)71-81
Number of pages11
JournalBioEssays
Volume32
Issue number1
DOIs
StatePublished - 2010
Externally publishedYes

Fingerprint

Population Genetics
Plasticity
Costs and Cost Analysis
Population Dynamics
Costs
Maintenance
Gene Expression
Mutation Accumulation
Gene expression

Keywords

  • Costs and limits
  • Development
  • Modularity
  • Mutation accumulation
  • Phenotypic plasticity
  • Pleiotropy
  • Relaxed selection

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Toward a population genetic framework of developmental evolution : The costs, limits, and consequences of phenotypic plasticity. / Snell-Rood, Emilie C.; Van Dyken, James; Cruickshank, Tami; Wade, Michael J.; Moczek, Armin P.

In: BioEssays, Vol. 32, No. 1, 2010, p. 71-81.

Research output: Contribution to journalArticle

Snell-Rood, Emilie C. ; Van Dyken, James ; Cruickshank, Tami ; Wade, Michael J. ; Moczek, Armin P. / Toward a population genetic framework of developmental evolution : The costs, limits, and consequences of phenotypic plasticity. In: BioEssays. 2010 ; Vol. 32, No. 1. pp. 71-81.
@article{61c9c0d42b314824ae756b3701ca56b0,
title = "Toward a population genetic framework of developmental evolution: The costs, limits, and consequences of phenotypic plasticity",
abstract = "Adaptive phenotypic plasticity allows organisms to cope with environmental variability, and yet, despite its adaptive significance, phenotypic plasticity is neither ubiquitous nor infinite. In this review, we merge developmental and population genetic perspectives to explore costs and limits on the evolution of plasticity. Specifically, we focus on the role of modularity in developmental genetic networks as a mechanism underlying phenotypic plasticity, and apply to it lessons learned from population genetic theory on the interplay between relaxed selection and mutation accumulation. We argue that the environmental specificity of gene expression and the associated reduction in pleiotropic constraints drive a fundamental tradeoff between the range of plasticity that can be accommodated and mutation accumulation in alternative developmental networks. This tradeoff has broad implications for understanding the origin and maintenance of plasticity and may contribute to a better understanding of the role of plasticity in the origin, diversification, and loss of phenotypic diversity.",
keywords = "Costs and limits, Development, Modularity, Mutation accumulation, Phenotypic plasticity, Pleiotropy, Relaxed selection",
author = "Snell-Rood, {Emilie C.} and {Van Dyken}, James and Tami Cruickshank and Wade, {Michael J.} and Moczek, {Armin P.}",
year = "2010",
doi = "10.1002/bies.200900132",
language = "English (US)",
volume = "32",
pages = "71--81",
journal = "BioEssays",
issn = "0265-9247",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

TY - JOUR

T1 - Toward a population genetic framework of developmental evolution

T2 - The costs, limits, and consequences of phenotypic plasticity

AU - Snell-Rood, Emilie C.

AU - Van Dyken, James

AU - Cruickshank, Tami

AU - Wade, Michael J.

AU - Moczek, Armin P.

PY - 2010

Y1 - 2010

N2 - Adaptive phenotypic plasticity allows organisms to cope with environmental variability, and yet, despite its adaptive significance, phenotypic plasticity is neither ubiquitous nor infinite. In this review, we merge developmental and population genetic perspectives to explore costs and limits on the evolution of plasticity. Specifically, we focus on the role of modularity in developmental genetic networks as a mechanism underlying phenotypic plasticity, and apply to it lessons learned from population genetic theory on the interplay between relaxed selection and mutation accumulation. We argue that the environmental specificity of gene expression and the associated reduction in pleiotropic constraints drive a fundamental tradeoff between the range of plasticity that can be accommodated and mutation accumulation in alternative developmental networks. This tradeoff has broad implications for understanding the origin and maintenance of plasticity and may contribute to a better understanding of the role of plasticity in the origin, diversification, and loss of phenotypic diversity.

AB - Adaptive phenotypic plasticity allows organisms to cope with environmental variability, and yet, despite its adaptive significance, phenotypic plasticity is neither ubiquitous nor infinite. In this review, we merge developmental and population genetic perspectives to explore costs and limits on the evolution of plasticity. Specifically, we focus on the role of modularity in developmental genetic networks as a mechanism underlying phenotypic plasticity, and apply to it lessons learned from population genetic theory on the interplay between relaxed selection and mutation accumulation. We argue that the environmental specificity of gene expression and the associated reduction in pleiotropic constraints drive a fundamental tradeoff between the range of plasticity that can be accommodated and mutation accumulation in alternative developmental networks. This tradeoff has broad implications for understanding the origin and maintenance of plasticity and may contribute to a better understanding of the role of plasticity in the origin, diversification, and loss of phenotypic diversity.

KW - Costs and limits

KW - Development

KW - Modularity

KW - Mutation accumulation

KW - Phenotypic plasticity

KW - Pleiotropy

KW - Relaxed selection

UR - http://www.scopus.com/inward/record.url?scp=74949103986&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74949103986&partnerID=8YFLogxK

U2 - 10.1002/bies.200900132

DO - 10.1002/bies.200900132

M3 - Article

VL - 32

SP - 71

EP - 81

JO - BioEssays

JF - BioEssays

SN - 0265-9247

IS - 1

ER -