Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer

H. B. Niell; G. M. Palmieri; C. L. Neely; T. A. Maxwell; S. C. Hopkins; M. S. Soloway

doi:10.1001/archinte.143.10.1925

Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer

H. B. Niell, G. M. Palmieri, C. L. Neely, T. A. Maxwell, S. C. Hopkins, M. S. Soloway

Research output: Contribution to journal › Article › peer-review

Abstract

The postabsorptive urinary total (T), dialyzable (D), and nondialyzable (ND) hydroxyproline (HYPRO) tests were evaluated to determine whether the patterns of excretion varied according to the predominance of osteoblastic v osteolytic bone involvement in 58 patients with neoplastic disease. In patients with osteolytic lesions from multiple myeloma, elevated T and D levels with normal ND HYPRO values were observed, along with elevated D/ND ratios. In prostate cancer, the T, D, and ND values were all elevated and the D/ND ratio was normal. Patients with Hodgkin's disease had elevated T, D, and ND HYPRO levels, and the D/ND ratio was in the range of patients with prostate cancer. The data suggest that these collagen markers may be useful in the long-term evaluation of these neoplasms in patients.

Original language	English
Pages (from-to)	1925-1927
Number of pages	3
Journal	Archives of Internal Medicine
Volume	143
Issue number	10
DOIs	https://doi.org/10.1001/archinte.143.10.1925
State	Published - Nov 26 1983
Externally published	Yes

ASJC Scopus subject areas

Internal Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1001/archinte.143.10.1925

Cite this

@article{ee585667f007430d9fd3beb90910d8e4,

title = "Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer",

abstract = "The postabsorptive urinary total (T), dialyzable (D), and nondialyzable (ND) hydroxyproline (HYPRO) tests were evaluated to determine whether the patterns of excretion varied according to the predominance of osteoblastic v osteolytic bone involvement in 58 patients with neoplastic disease. In patients with osteolytic lesions from multiple myeloma, elevated T and D levels with normal ND HYPRO values were observed, along with elevated D/ND ratios. In prostate cancer, the T, D, and ND values were all elevated and the D/ND ratio was normal. Patients with Hodgkin's disease had elevated T, D, and ND HYPRO levels, and the D/ND ratio was in the range of patients with prostate cancer. The data suggest that these collagen markers may be useful in the long-term evaluation of these neoplasms in patients.",

author = "Niell, {H. B.} and Palmieri, {G. M.} and Neely, {C. L.} and Maxwell, {T. A.} and Hopkins, {S. C.} and Soloway, {M. S.}",

year = "1983",

month = nov,

day = "26",

doi = "10.1001/archinte.143.10.1925",

language = "English",

volume = "143",

pages = "1925--1927",

journal = "Archives of internal medicine (Chicago, Ill. : 1908)",

issn = "2168-6106",

publisher = "American Medical Association",

number = "10",

}

TY - JOUR

T1 - Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer

AU - Niell, H. B.

AU - Palmieri, G. M.

AU - Neely, C. L.

AU - Maxwell, T. A.

AU - Hopkins, S. C.

AU - Soloway, M. S.

PY - 1983/11/26

Y1 - 1983/11/26

N2 - The postabsorptive urinary total (T), dialyzable (D), and nondialyzable (ND) hydroxyproline (HYPRO) tests were evaluated to determine whether the patterns of excretion varied according to the predominance of osteoblastic v osteolytic bone involvement in 58 patients with neoplastic disease. In patients with osteolytic lesions from multiple myeloma, elevated T and D levels with normal ND HYPRO values were observed, along with elevated D/ND ratios. In prostate cancer, the T, D, and ND values were all elevated and the D/ND ratio was normal. Patients with Hodgkin's disease had elevated T, D, and ND HYPRO levels, and the D/ND ratio was in the range of patients with prostate cancer. The data suggest that these collagen markers may be useful in the long-term evaluation of these neoplasms in patients.

AB - The postabsorptive urinary total (T), dialyzable (D), and nondialyzable (ND) hydroxyproline (HYPRO) tests were evaluated to determine whether the patterns of excretion varied according to the predominance of osteoblastic v osteolytic bone involvement in 58 patients with neoplastic disease. In patients with osteolytic lesions from multiple myeloma, elevated T and D levels with normal ND HYPRO values were observed, along with elevated D/ND ratios. In prostate cancer, the T, D, and ND values were all elevated and the D/ND ratio was normal. Patients with Hodgkin's disease had elevated T, D, and ND HYPRO levels, and the D/ND ratio was in the range of patients with prostate cancer. The data suggest that these collagen markers may be useful in the long-term evaluation of these neoplasms in patients.

UR - http://www.scopus.com/inward/record.url?scp=0020515062&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020515062&partnerID=8YFLogxK

U2 - 10.1001/archinte.143.10.1925

DO - 10.1001/archinte.143.10.1925

M3 - Article

C2 - 6625779

VL - 143

SP - 1925

EP - 1927

JO - Archives of internal medicine (Chicago, Ill. : 1908)

JF - Archives of internal medicine (Chicago, Ill. : 1908)

SN - 2168-6106

IS - 10

ER -

Total, dialyzable, and nondialyzable postabsorptive hydroxyproline. Values in patients with cancer

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this