Tissue plasminogen activator for acute ischemic stroke in patients with unruptured cerebral aneurysms

Luis D'Olhaberriague, Nishit Joshi, Seement Chaturvedi, Panayiotis Mitsias, William Coplin, Christopher A. Lewandowski, Suresh C. Patel, Steven R. Levine

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Intracranial hemorrhage (ICH) is the most feared complication of thrombolytic therapy for acute ischemic stroke. There are limited data on the risks of thrombolysis in patients with asymptomatic intracranial aneurysm. We report 2 adults with signs of hemispheric ischemia who were successfully treated with intravenous tissue plasminogen activator (t-PA), despite the presence of asymptomatic intracranial aneurysm. The presence of an asymptomatic intracranial aneurysm may not necessarily preclude a good outcome from acute ischemic stroke treated with rt-PA. Selected patients harboring incidental, unruptured intracranial aneurysm may benefit from thrombolytics.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalJournal of Stroke and Cerebrovascular Diseases
Volume9
Issue number4
DOIs
StatePublished - Jul 2000
Externally publishedYes

Keywords

  • Intracranial aneurysm
  • Ischemic stroke
  • Thrombolysis
  • Tissue plasminogen activator

ASJC Scopus subject areas

  • Surgery
  • Rehabilitation
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Tissue plasminogen activator for acute ischemic stroke in patients with unruptured cerebral aneurysms'. Together they form a unique fingerprint.

  • Cite this

    D'Olhaberriague, L., Joshi, N., Chaturvedi, S., Mitsias, P., Coplin, W., Lewandowski, C. A., Patel, S. C., & Levine, S. R. (2000). Tissue plasminogen activator for acute ischemic stroke in patients with unruptured cerebral aneurysms. Journal of Stroke and Cerebrovascular Diseases, 9(4), 181-184. https://doi.org/10.1053/jscd.2000.7213