Tissue engineering of the penis

Manish N. Patel, Anthony Atala

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Congenital disorders, cancer, trauma, or other conditions of the genitourinary tract can lead to significant organ damage or loss of function, necessitating eventual reconstruction or replacement of the damaged structures. However, current reconstructive techniques are limited by issues of tissue availability and compatibility. Physicians and scientists have begun to explore tissue engineering and regenerative medicine strategies for repair and reconstruction of the genitourinary tract. Tissue engineering allows the development of biological substitutes which could potentially restore normal function. Tissue engineering efforts designed to treat or replace most organs are currently being undertaken. Most of these efforts have occurred within the past decade. However, before these engineering techniques can be applied to humans, further studies are needed to ensure the safety and efficacy of these new materials. Recent progress suggests that engineered urologic tissues and cell therapy may soon have clinical applicability.

Original languageEnglish
Pages (from-to)2567-2578
Number of pages12
JournalTheScientificWorldJournal
Volume11
DOIs
StatePublished - Dec 1 2011
Externally publishedYes

Fingerprint

Penis
Tissue Engineering
Tissue engineering
Cell- and Tissue-Based Therapy
engineering
Tissue
Reconstruction (structural)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Histocompatibility
Regenerative Medicine
Repair
Availability
Physicians
Safety
medicine
Wounds and Injuries
repair
cancer
replacement
tissue

Keywords

  • extracellular matrix (ECM)
  • genitourinary tract
  • penis
  • regenerative medicine
  • scaffold
  • tissue engineering

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)
  • Medicine(all)

Cite this

Tissue engineering of the penis. / Patel, Manish N.; Atala, Anthony.

In: TheScientificWorldJournal, Vol. 11, 01.12.2011, p. 2567-2578.

Research output: Contribution to journalArticle

Patel, Manish N. ; Atala, Anthony. / Tissue engineering of the penis. In: TheScientificWorldJournal. 2011 ; Vol. 11. pp. 2567-2578.
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