Tissue Engineering of the Nervous System

Paul D. Dalton, Alan R. Harvey, Martin Oudega, Giles W. Plant

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Scopus citations

Abstract

This chapter covers the challenges and approaches associated with tissue engineering (TE) in the peripheral and central nervous system. The molecular and cellular environment of each tissue demands particular emphasis, as do the natural anatomical structure and relevant animal models for repair. Given the complex interactions between neurons, glia, and the immune system in vivo, it is important to note that to date TE has only encompassed limited areas of neuroscience. The induction of neurite outgrowth and nerve regeneration has attracted the most attention, while materials for neuroprotection strategies have so far been more limited in their application.

Original languageEnglish (US)
Title of host publicationTissue Engineering: Second Edition
PublisherElsevier Inc.
Pages583-625
Number of pages43
ISBN (Print)9780124201453
DOIs
StatePublished - Dec 10 2014
Externally publishedYes

Keywords

  • Cell transplantation
  • Cochlear
  • Neuroprosthesis
  • Peripheral nerve injury
  • Retina
  • Spinal cord injury

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Dalton, P. D., Harvey, A. R., Oudega, M., & Plant, G. W. (2014). Tissue Engineering of the Nervous System. In Tissue Engineering: Second Edition (pp. 583-625). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-420145-3.00017-1