TIN-X: target importance and novelty explorer

Daniel C. Cannon; Jeremy J. Yang; Stephen L. Mathias; Oleg Ursu; Subramani Mani; Anna Waller; Stephan C Schuerer; Lars Juhl Jensen; Larry A. Sklar; Cristian G. Bologa; Tudor I. Oprea

doi:10.1093/bioinformatics/btx200

TIN-X: target importance and novelty explorer

Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Oleg Ursu, Subramani Mani, Anna Waller, Stephan C Schuerer, Lars Juhl Jensen, Larry A. Sklar, Cristian G. Bologa, Tudor I. Oprea

Molecular and Cellular Pharmacology

Research output: Contribution to journal › Article

5 Scopus citations

Abstract

Motivation: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins.

Results: We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty.

Availability and Implementation: http://www.newdrugtargets.org.

Contact: cbologa@salud.unm.edu.

Original language	English (US)
Pages (from-to)	2601-2603
Number of pages	3
Journal	Bioinformatics (Oxford, England)
Volume	33
Issue number	16
DOIs	https://doi.org/10.1093/bioinformatics/btx200
State	Published - Aug 15 2017

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ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

Cite this

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., Schuerer, S. C., Jensen, L. J., Sklar, L. A., Bologa, C. G., & Oprea, T. I. (2017). TIN-X: target importance and novelty explorer. Bioinformatics (Oxford, England), 33(16), 2601-2603. https://doi.org/10.1093/bioinformatics/btx200

TIN-X : target importance and novelty explorer. / Cannon, Daniel C.; Yang, Jeremy J.; Mathias, Stephen L.; Ursu, Oleg; Mani, Subramani; Waller, Anna; Schuerer, Stephan C; Jensen, Lars Juhl; Sklar, Larry A.; Bologa, Cristian G.; Oprea, Tudor I.

In: Bioinformatics (Oxford, England), Vol. 33, No. 16, 15.08.2017, p. 2601-2603.

Research output: Contribution to journal › Article

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10.1093/bioinformatics/btx200