TIN-X: target importance and novelty explorer

Daniel C. Cannon, Jeremy J. Yang, Stephen L. Mathias, Oleg Ursu, Subramani Mani, Anna Waller, Stephan C Schuerer, Lars Juhl Jensen, Larry A. Sklar, Cristian G. Bologa, Tudor I. Oprea

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Motivation: The increasing amount of peer-reviewed manuscripts requires the development of specific mining tools to facilitate the visual exploration of evidence linking diseases and proteins.

Results: We developed TIN-X, the Target Importance and Novelty eXplorer, to visualize the association between proteins and diseases, based on text mining data processed from scientific literature. In the current implementation, TIN-X supports exploration of data for G-protein coupled receptors, kinases, ion channels, and nuclear receptors. TIN-X supports browsing and navigating across proteins and diseases based on ontology classes, and displays a scatter plot with two proposed new bibliometric statistics: Importance and Novelty.

Availability and Implementation: http://www.newdrugtargets.org.

Contact: cbologa@salud.unm.edu.

Original languageEnglish (US)
Pages (from-to)2601-2603
Number of pages3
JournalBioinformatics (Oxford, England)
Volume33
Issue number16
DOIs
StatePublished - Aug 15 2017

Fingerprint

Proteins
Protein
Receptor
Target
G-Protein-Coupled Receptor Kinases
Bibliometrics
Scatter diagram
Literature
G Protein
Ion Channels
Data Mining
Manuscripts
Text Mining
Browsing
Cytoplasmic and Nuclear Receptors
Linking
Data mining
Ontology
Mining
Availability

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

Cite this

Cannon, D. C., Yang, J. J., Mathias, S. L., Ursu, O., Mani, S., Waller, A., ... Oprea, T. I. (2017). TIN-X: target importance and novelty explorer. Bioinformatics (Oxford, England), 33(16), 2601-2603. https://doi.org/10.1093/bioinformatics/btx200

TIN-X : target importance and novelty explorer. / Cannon, Daniel C.; Yang, Jeremy J.; Mathias, Stephen L.; Ursu, Oleg; Mani, Subramani; Waller, Anna; Schuerer, Stephan C; Jensen, Lars Juhl; Sklar, Larry A.; Bologa, Cristian G.; Oprea, Tudor I.

In: Bioinformatics (Oxford, England), Vol. 33, No. 16, 15.08.2017, p. 2601-2603.

Research output: Contribution to journalArticle

Cannon, DC, Yang, JJ, Mathias, SL, Ursu, O, Mani, S, Waller, A, Schuerer, SC, Jensen, LJ, Sklar, LA, Bologa, CG & Oprea, TI 2017, 'TIN-X: target importance and novelty explorer', Bioinformatics (Oxford, England), vol. 33, no. 16, pp. 2601-2603. https://doi.org/10.1093/bioinformatics/btx200
Cannon DC, Yang JJ, Mathias SL, Ursu O, Mani S, Waller A et al. TIN-X: target importance and novelty explorer. Bioinformatics (Oxford, England). 2017 Aug 15;33(16):2601-2603. https://doi.org/10.1093/bioinformatics/btx200
Cannon, Daniel C. ; Yang, Jeremy J. ; Mathias, Stephen L. ; Ursu, Oleg ; Mani, Subramani ; Waller, Anna ; Schuerer, Stephan C ; Jensen, Lars Juhl ; Sklar, Larry A. ; Bologa, Cristian G. ; Oprea, Tudor I. / TIN-X : target importance and novelty explorer. In: Bioinformatics (Oxford, England). 2017 ; Vol. 33, No. 16. pp. 2601-2603.
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