Timing of adjuvant and neoadjuvant therapy in colorectal cancers

Soley Bayraktar, Ulas Bayraktar, Caio Rocha-Lima

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Surgery remains the only curative therapy for colorectal cancer (CRC); however, several studies have proved that adjuvant chemotherapy improves the curative rate. A growing body of evidence indicates that significant deviations from recommended treatment plans are frequent. Patients may experience delays in the administration of adjuvant chemotherapy that can reduce its survival benefit. To date, few studies have examined factors associated with the timing of adjuvant chemotherapy or have described the effects of delayed therapy on overall survival. In this review, we discuss the extent and predictors of delay in administration of adjuvant chemotherapy as well as the relationship between timing and outcomes in CRC.

Original languageEnglish (US)
Pages (from-to)144-149
Number of pages6
JournalClinical colorectal cancer
Issue number3
StatePublished - Jul 1 2010


  • Anastomosis
  • Hepatic artery infusion
  • Portal vein infusion
  • Wound healing

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology


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