Abstract
Surgery remains the only curative therapy for colorectal cancer (CRC); however, several studies have proved that adjuvant chemotherapy improves the curative rate. A growing body of evidence indicates that significant deviations from recommended treatment plans are frequent. Patients may experience delays in the administration of adjuvant chemotherapy that can reduce its survival benefit. To date, few studies have examined factors associated with the timing of adjuvant chemotherapy or have described the effects of delayed therapy on overall survival. In this review, we discuss the extent and predictors of delay in administration of adjuvant chemotherapy as well as the relationship between timing and outcomes in CRC.
| Original language | English |
|---|---|
| Pages (from-to) | 144-149 |
| Number of pages | 6 |
| Journal | Clinical Colorectal Cancer |
| Volume | 9 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 1 2010 |
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Keywords
- Anastomosis
- Hepatic artery infusion
- Portal vein infusion
- Wound healing
ASJC Scopus subject areas
- Oncology
- Gastroenterology
Cite this
Timing of adjuvant and neoadjuvant therapy in colorectal cancers. / Bayraktar, Soley; Bayraktar, Ulas; Rocha-Lima, Caio.
In: Clinical Colorectal Cancer, Vol. 9, No. 3, 01.07.2010, p. 144-149.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Timing of adjuvant and neoadjuvant therapy in colorectal cancers
AU - Bayraktar, Soley
AU - Bayraktar, Ulas
AU - Rocha-Lima, Caio
PY - 2010/7/1
Y1 - 2010/7/1
N2 - Surgery remains the only curative therapy for colorectal cancer (CRC); however, several studies have proved that adjuvant chemotherapy improves the curative rate. A growing body of evidence indicates that significant deviations from recommended treatment plans are frequent. Patients may experience delays in the administration of adjuvant chemotherapy that can reduce its survival benefit. To date, few studies have examined factors associated with the timing of adjuvant chemotherapy or have described the effects of delayed therapy on overall survival. In this review, we discuss the extent and predictors of delay in administration of adjuvant chemotherapy as well as the relationship between timing and outcomes in CRC.
AB - Surgery remains the only curative therapy for colorectal cancer (CRC); however, several studies have proved that adjuvant chemotherapy improves the curative rate. A growing body of evidence indicates that significant deviations from recommended treatment plans are frequent. Patients may experience delays in the administration of adjuvant chemotherapy that can reduce its survival benefit. To date, few studies have examined factors associated with the timing of adjuvant chemotherapy or have described the effects of delayed therapy on overall survival. In this review, we discuss the extent and predictors of delay in administration of adjuvant chemotherapy as well as the relationship between timing and outcomes in CRC.
KW - Anastomosis
KW - Hepatic artery infusion
KW - Portal vein infusion
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=77955005391&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955005391&partnerID=8YFLogxK
U2 - 10.3816/CCC.2010.n.019
DO - 10.3816/CCC.2010.n.019
M3 - Article
VL - 9
SP - 144
EP - 149
JO - Clinical Colorectal Cancer
JF - Clinical Colorectal Cancer
SN - 1533-0028
IS - 3
ER -