Trastornos en la percepción del tiempo en pacientes con alteraciones dopaminérgicas

Introduction Cognitive ability to perceive time has been a subject of investigation throughout history and time-perception abnormalities have been described in different Neurological and Psychiatric disorders. Objective To assess and compare time-perception in patients with PD and ADD. Materials and methods Outpatients with previous diagnosis of PD or ADD were studied with modified Bueti and Walsh's cognitive battery (Bueti and Walsh 2010, Ganzenmuller E 2012), to analyze time-perception. Results There was a significant difference in estimation of time between both groups, when testing short intervals (3 seconds as reference. P=.001). Under-estimation of time was constant in all groups, but more prominent in patients with PD. Patients with ADD showed anticipation in most cases and learning effect was limited. Conclusion Time-perception alterations were found in patients with PD and ADD, with more prominent under-estimation in patients with PD and anticipation in patients with ADD. More research in this subject may help to better understand the role of dopamine in the biological clock.