Time-lapse imaging of neural development: Zebrafish lead the way into the fourth dimension

Sandra Rieger, Fang Wang, Alvaro Sagasti

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Time-lapse imaging is often the only way to appreciate fully the many dynamic cell movements critical to neural development. Zebrafish possess many advantages that make them the best vertebrate model organism for live imaging of dynamic development events. This review will discuss technical considerations of time-lapse imaging experiments in zebrafish, describe selected examples of imaging studies in zebrafish that revealed new features or principles of neural development, and consider the promise and challenges of future time-lapse studies of neural development in zebrafish embryos and adults.

Original languageEnglish (US)
Pages (from-to)534-545
Number of pages12
JournalGenesis
Volume49
Issue number7
DOIs
StatePublished - Jul 2011
Externally publishedYes

Keywords

  • Imaging
  • Neural development
  • Neurons
  • Time-lapse
  • Zebrafish

ASJC Scopus subject areas

  • Genetics
  • Endocrinology
  • Cell Biology

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