Thyrotropin-releasing hormone and amphetamine: A comparison of pharmacological profiles in animals

P. J. Manberg, C. B. Nemeroff, A. J. Prange

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


1. 1. The pharmacological effects of TRH are compared to those produced by d-amphetamine in an attempt to elucidate the mechanisms underlying the activity of this endogenous peptide. 2. 2. Although numerous amphetamine-like actions have been attributed to TRH, several differences have been noted between these compounds and are discussed. 3. 3. At present, it is impossible to propose a single mechanism of action to explain the behavioral effects of TRH.

Original languageEnglish (US)
Pages (from-to)303-314
Number of pages12
JournalProgress in Neuro-Psychopharmacology
Issue number4
StatePublished - 1979
Externally publishedYes


  • d-amphetamine
  • pharmacological profiles
  • thyrotropin-releasing hormone

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Medicine(all)


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