Thyroid Hormone Receptor Subtypes and Their Interaction with Steroid Receptor Coactivators

Roy E. Weiss, Helton E. Ramos

Research output: Chapter in Book/Report/Conference proceedingChapter

15 Scopus citations

Abstract

Thyroid hormone (TH) is required for normal growth, development, and metabolism in metazoans. To influence this broad range of physiologic actions, TH is necessarily involved in the regulation of a multitude of genes in virtually every tissue. The diversity of gene expression regulation in response to TH is mediated through specific intranuclear TH receptors (TRs) and other nuclear coregulators. This chapter reviews TRs and nuclear coregulators, specifically coactivators, based on in vivo data from knockout (KO) mouse models.

Original languageEnglish (US)
Title of host publicationNuclear Receptor Coregulators
Pages185-207
Number of pages23
DOIs
StatePublished - Dec 1 2004
Externally publishedYes

Publication series

NameVitamins and Hormones
Volume68
ISSN (Print)0083-6729

ASJC Scopus subject areas

  • Physiology
  • Endocrinology

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  • Cite this

    Weiss, R. E., & Ramos, H. E. (2004). Thyroid Hormone Receptor Subtypes and Their Interaction with Steroid Receptor Coactivators. In Nuclear Receptor Coregulators (pp. 185-207). (Vitamins and Hormones; Vol. 68). https://doi.org/10.1016/S0083-6729(04)68006-X