To the Editor: The results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) trial, reported by Topol et al. (Sept. 3 issue), suggest that performing immediate angioplasty in patients with high-grade residual coronary stenosis after thrombolytic therapy is not generally warranted in view of the finding that neither global nor regional function is different in patients undergoing immediate as compared with delayed angioplasty. Delaying angioplasty in patients with initially successful thrombolysis but with high-grade residual stenosis did, however, lead to a higher incidence of emergency angioplasty or elective or urgent bypass surgery than in patients undergoing immediate angioplasty. The.
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