Thrombocytosis and hyposplenism in an infant with fetal hydantoin syndrome

Ofelia Alvarez, John H. Miller, Thomas D. Coates

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


An infant boy with fetal hydantoin syndrome was evaluated for the finding of thrombocytosis. Delayed splenic maturation was identified by a decreased splenic uptake of 99mTc sulfur colloid and by an increased number of pitted erythrocytes at 6 months of age. We speculate that the patient's thrombocytosis may be related to delayed maturation of splenic function and conclude that hyposplenism and secondary thrombocytosis may be associated with fetal hydantoin syndrome.

Original languageEnglish (US)
Pages (from-to)62-65
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Issue number1
StatePublished - Jan 1 1992
Externally publishedYes


  • Hydantoin
  • Hyposplenism
  • Thrombocytosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


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