Three-year results of the prospective evaluation of radial keratotomy (PERK) study

G. O. Waring, M. J. Lynn, William W Culbertson, P. R. Laibson, R. D. Lindstrom, M. B. McDonald, W. D. Myers, S. A. Obstbaum, J. J. Rowsey, D. J. Schanzlin

Research output: Contribution to journalArticle

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Abstract

The Prospective Evaluation of Radial Keratotomy (PERK) study is a nine-center clinical trial of a standardized technique of radial keratotomy in 435 patients who had simple myopia with a preoperative refractive error between -2.00 and -8.00 diopters (D). The authors report results for one eye of each patient. The surgical technique consisted of eight incisions using a diamond micrometer knife with the blade length determined by intraoperative ultrasonic pachymetry and the diameter of the central clear zone determined by the preoperative refractive error. At 3 years after surgery, 58% of eyes had refractive error within 1.00 D of emmetropia; 26% were undercorrected and 16% were overcorrected by more than 1.00 D. Uncorrected visual acuity was 20/40 or better in 76% of eyes. The operation was more effective in eyes with a preoperative refractive error between -2.00 and -4.37 D. Between 1 and 3 years after surgery, the refractive error changed by 1.00 D or more in 12% of eyes, indicating a lack of stability in some eyes. In the 435 eyes, there was a small number of complications including six eyes that lost two or three lines of best-corrected acuity, 16 that experienced vascularization of the incisions, 2 that had delayed bacterial keratitis, and 4 that had recurrent epithelial erosions.

Original languageEnglish
Pages (from-to)1339-1354
Number of pages16
JournalOphthalmology
Volume94
Issue number10
StatePublished - Jan 1 1987
Externally publishedYes

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Radial Keratotomy
Refractive Errors
Emmetropia
Diamond
Keratitis
Myopia
Ultrasonics
Visual Acuity
Clinical Trials

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Waring, G. O., Lynn, M. J., Culbertson, W. W., Laibson, P. R., Lindstrom, R. D., McDonald, M. B., ... Schanzlin, D. J. (1987). Three-year results of the prospective evaluation of radial keratotomy (PERK) study. Ophthalmology, 94(10), 1339-1354.

Three-year results of the prospective evaluation of radial keratotomy (PERK) study. / Waring, G. O.; Lynn, M. J.; Culbertson, William W; Laibson, P. R.; Lindstrom, R. D.; McDonald, M. B.; Myers, W. D.; Obstbaum, S. A.; Rowsey, J. J.; Schanzlin, D. J.

In: Ophthalmology, Vol. 94, No. 10, 01.01.1987, p. 1339-1354.

Research output: Contribution to journalArticle

Waring, GO, Lynn, MJ, Culbertson, WW, Laibson, PR, Lindstrom, RD, McDonald, MB, Myers, WD, Obstbaum, SA, Rowsey, JJ & Schanzlin, DJ 1987, 'Three-year results of the prospective evaluation of radial keratotomy (PERK) study', Ophthalmology, vol. 94, no. 10, pp. 1339-1354.
Waring GO, Lynn MJ, Culbertson WW, Laibson PR, Lindstrom RD, McDonald MB et al. Three-year results of the prospective evaluation of radial keratotomy (PERK) study. Ophthalmology. 1987 Jan 1;94(10):1339-1354.
Waring, G. O. ; Lynn, M. J. ; Culbertson, William W ; Laibson, P. R. ; Lindstrom, R. D. ; McDonald, M. B. ; Myers, W. D. ; Obstbaum, S. A. ; Rowsey, J. J. ; Schanzlin, D. J. / Three-year results of the prospective evaluation of radial keratotomy (PERK) study. In: Ophthalmology. 1987 ; Vol. 94, No. 10. pp. 1339-1354.
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