@article{7761feb6225441648a4da0a062e1f9e1,
title = "Three-Dimensional Spectral-Domain Optical Coherence Tomography Images of the Retina in the Presence of Epiretinal Membranes",
abstract = "Purpose: To study the inner surface of the retina in the presence of epiretinal membranes (ERMs) using a prototype spectral-domain optical coherence tomography (SD-OCT) device. Design: Small case series, performed in the Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, from August 2005 through December 2006. Method: An 8-μm axial-resolution SD-OCT instrument was used to scan the eyes of patients diagnosed with ERM. The ERM and the internal limiting membrane (ILM) were segmented separately to evaluate the traction caused by the ERM on the retina. It was then possible to reconstruct the ILM and ERM surfaces in 3-dimensional space and to obtain corresponding retinal thickness maps. Results: SD-OCT B scans showed the points of attachment of the ERM to the ILM. Segmented surface maps of the ERM produced very smooth sheets, whereas those of the ILM presented wrinkles under and around the ERM. Conclusions: SD-OCT revealed the geometry of retinal traction in eyes with ERM and may be useful in understanding further the pathologic features of these lesions.",
author = "Legarreta, {John E.} and Giovanni Gregori and Knighton, {Robert W.} and Punjabi, {Omar S.} and Lalwani, {Geeta A.} and Puliafito, {Carmen A.}",
note = "Funding Information: This study was supported in part by Research to Prevent Blindness, Inc, New York, New York; Research funding provided in part by a Grant from Carl Zeiss Meditec, Inc, Dublin, California. (Drs Punjabi, Legarreta, Gregori, Knighton, and Puliafito); and Grant P30 EY014801 from the National Institutes of Health, Bethesda, Maryland. Dr Puliafito is a Research and Clinical Consultant for Carl Zeiss Meditec, Inc. Involved in design and conduct of study (J.L., G.G., R.K., C.P.); collection of data (J.L., G.G., R.K., G.L., C.P.); management, analysis, and interpretation of the data (J.L., G.G., R.K., C.P.); preparation of the manuscript (J.L., G.G., R.K.); and review and approval of the manuscript (J.L., G.G., R.K., O.P., G.L., C.P.). Approval of the appropriate institutional review board was obtained and the study was compliant with the Declaration of Helsinki. Written informed consent was obtained from all subjects before acquiring the images, as well as Health Insurance Portability and Accountability Act documentation. ",
year = "2008",
month = jun,
doi = "10.1016/j.ajo.2008.01.014",
language = "English (US)",
volume = "145",
pages = "1023--1030.e1",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "6",
}