Thoracoabdominal compression and respiratory system compliance in HIV- infected infants

Arnold C G Platzker, Andrew Colin, Xin C. Chen, Peter Hiatt, Janice Hunter, Anatassios C. Koumbourlis, Mark D. Schluchter, Andrew Ting, Mary Ellen Wohl

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The thoracoabdominal compression technique (TAC) is used to measure expiratory flow in infants. We investigated whether TAC caused a change in total thoracic compliance (Crs), resistance (Rrs), and respiratory system time constant (Trs). We studied 41 infants (mean age, 12.4 mo; SD, 7.5) from five centers studying longitudinal lung and cardiovascular function of infants from HIV-infected mothers. We measured Crs, Rrs, and Trs before and after TAC. Changes in Crs, Rrs, and Trs after TAC were not dependent on the length of time since TAC. Crs and Trs were reduced after TAC, p = 0.013 and p = 0.003, respectively, whereas Rrs did not change. When compared with uninfected infants, HIV-infected infants had a larger post-pre TAC percent decline in Crs (p = 0.003) and a post-pre TAC rise in mean Rrs (p = 0.03). These differences remained significant after adjusting for sex and age. When performing infant pulmonary function testing, TAC itself produces a temporary decrease in Crs and Trs that is more significant in infants at risk for abnormal lung volume or compliance. Therefore, the sequence of performing the infant lung function parameters should be the same each time the testing is repeated with TAC as the last parameter tested at each testing session.

Original languageEnglish
Pages (from-to)1567-1571
Number of pages5
JournalAmerican Journal of Respiratory and Critical Care Medicine
Volume161
Issue number5
StatePublished - Jun 14 2000
Externally publishedYes

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Respiratory System
Compliance
HIV
Lung
Thorax
Mothers

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Platzker, A. C. G., Colin, A., Chen, X. C., Hiatt, P., Hunter, J., Koumbourlis, A. C., ... Wohl, M. E. (2000). Thoracoabdominal compression and respiratory system compliance in HIV- infected infants. American Journal of Respiratory and Critical Care Medicine, 161(5), 1567-1571.

Thoracoabdominal compression and respiratory system compliance in HIV- infected infants. / Platzker, Arnold C G; Colin, Andrew; Chen, Xin C.; Hiatt, Peter; Hunter, Janice; Koumbourlis, Anatassios C.; Schluchter, Mark D.; Ting, Andrew; Wohl, Mary Ellen.

In: American Journal of Respiratory and Critical Care Medicine, Vol. 161, No. 5, 14.06.2000, p. 1567-1571.

Research output: Contribution to journalArticle

Platzker, ACG, Colin, A, Chen, XC, Hiatt, P, Hunter, J, Koumbourlis, AC, Schluchter, MD, Ting, A & Wohl, ME 2000, 'Thoracoabdominal compression and respiratory system compliance in HIV- infected infants', American Journal of Respiratory and Critical Care Medicine, vol. 161, no. 5, pp. 1567-1571.
Platzker ACG, Colin A, Chen XC, Hiatt P, Hunter J, Koumbourlis AC et al. Thoracoabdominal compression and respiratory system compliance in HIV- infected infants. American Journal of Respiratory and Critical Care Medicine. 2000 Jun 14;161(5):1567-1571.
Platzker, Arnold C G ; Colin, Andrew ; Chen, Xin C. ; Hiatt, Peter ; Hunter, Janice ; Koumbourlis, Anatassios C. ; Schluchter, Mark D. ; Ting, Andrew ; Wohl, Mary Ellen. / Thoracoabdominal compression and respiratory system compliance in HIV- infected infants. In: American Journal of Respiratory and Critical Care Medicine. 2000 ; Vol. 161, No. 5. pp. 1567-1571.
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