Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao, Erika Parasido, Siddarth Rawal, Anthony Williams, Richard Schlegel, Stephen Liu, Chris Albanese, Richard J Cote, Ashutosh Agarwal, Ram Datar

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Original languageEnglish (US)
Pages (from-to)4277-4282
Number of pages6
JournalLab on a Chip - Miniaturisation for Chemistry and Biology
Volume15
Issue number22
DOIs
StatePublished - 2015

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Circulating Neoplastic Cells
Precision Medicine
Medicine
Tumors
Cells
Polymers
Blood
Recovery
Coatings
Temperature

ASJC Scopus subject areas

  • Biochemistry
  • Chemistry(all)
  • Bioengineering
  • Biomedical Engineering

Cite this

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications. / Ao, Zheng; Parasido, Erika; Rawal, Siddarth; Williams, Anthony; Schlegel, Richard; Liu, Stephen; Albanese, Chris; Cote, Richard J; Agarwal, Ashutosh; Datar, Ram.

In: Lab on a Chip - Miniaturisation for Chemistry and Biology, Vol. 15, No. 22, 2015, p. 4277-4282.

Research output: Contribution to journalArticle

Ao, Zheng ; Parasido, Erika ; Rawal, Siddarth ; Williams, Anthony ; Schlegel, Richard ; Liu, Stephen ; Albanese, Chris ; Cote, Richard J ; Agarwal, Ashutosh ; Datar, Ram. / Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications. In: Lab on a Chip - Miniaturisation for Chemistry and Biology. 2015 ; Vol. 15, No. 22. pp. 4277-4282.
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