Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao; Erika Parasido; Siddarth Rawal; Anthony Williams; Richard Schlegel; Stephen Liu; Chris Albanese; Richard J. Cote; Ashutosh Agarwal; Ram H. Datar

doi:10.1039/c5lc01024a

Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao, Erika Parasido, Siddarth Rawal, Anthony Williams, Richard Schlegel, Stephen Liu, Chris Albanese, Richard J. Cote, Ashutosh Agarwal, Ram H. Datar

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Original language	English (US)
Pages (from-to)	4277-4282
Number of pages	6
Journal	Lab on a Chip
Volume	15
Issue number	22
DOIs	https://doi.org/10.1039/c5lc01024a
State	Published - 2015

ASJC Scopus subject areas

Bioengineering
Biochemistry
Chemistry(all)
Biomedical Engineering

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10.1039/c5lc01024a

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Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications. / Ao, Zheng; Parasido, Erika; Rawal, Siddarth; Williams, Anthony; Schlegel, Richard; Liu, Stephen; Albanese, Chris; Cote, Richard J.; Agarwal, Ashutosh; Datar, Ram H.

In: Lab on a Chip, Vol. 15, No. 22, 2015, p. 4277-4282.

Research output: Contribution to journal › Article › peer-review

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abstract = "Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.",

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AU - Parasido, Erika

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AU - Schlegel, Richard

AU - Liu, Stephen

AU - Albanese, Chris

AU - Cote, Richard J.

AU - Agarwal, Ashutosh

AU - Datar, Ram H.

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Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Abstract

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