Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications

Zheng Ao, Erika Parasido, Siddarth Rawal, Anthony Williams, Richard Schlegel, Stephen Liu, Chris Albanese, Richard J. Cote, Ashutosh Agarwal, Ram H. Datar

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Stimulus responsive release of Circulating Tumor Cells (CTCs), with high recovery rates from their capture platform, is highly desirable for off-chip analyses. Here, we present a temperature responsive polymer coating method to achieve both release as well as culture of viable CTCs captured from patient blood samples.

Original languageEnglish (US)
Pages (from-to)4277-4282
Number of pages6
JournalLab on a Chip
Volume15
Issue number22
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Chemistry(all)
  • Biomedical Engineering

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  • Cite this

    Ao, Z., Parasido, E., Rawal, S., Williams, A., Schlegel, R., Liu, S., Albanese, C., Cote, R. J., Agarwal, A., & Datar, R. H. (2015). Thermoresponsive release of viable microfiltrated Circulating Tumor Cells (CTCs) for precision medicine applications. Lab on a Chip, 15(22), 4277-4282. https://doi.org/10.1039/c5lc01024a