Therapy of Ischemic Cerebral Vascular Disease

Martin M. Pincus, Michael Hennerici, Wolfgang Rautenberg, Lawrence J. Saidman, J. P. Kistler, Allan H. Ropper, Roberto Heros

Research output: Contribution to journalLetter

2 Scopus citations


To the Editor: A patient who has had a transient ischemic attack is by definition neurologically intact, at least when seen 24 hours after the event. The very concept that he has a disease — namely, threatened stroke — is based on statistical reasoning. In fact, several studies have shown that the majority of patients do not go on to have a completed stroke over the next year. In order to prove that any proposed therapy is better than “doing nothing,” it would seem to be incumbent on the proponents to prove that the probability of stroke or of a.

Original languageEnglish (US)
Pages (from-to)1124-1125
Number of pages2
JournalNew England Journal of Medicine
Issue number17
StatePublished - Oct 25 1984
Externally publishedYes


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Therapy of Ischemic Cerebral Vascular Disease. / Pincus, Martin M.; Hennerici, Michael; Rautenberg, Wolfgang; Saidman, Lawrence J.; Kistler, J. P.; Ropper, Allan H.; Heros, Roberto.

In: New England Journal of Medicine, Vol. 311, No. 17, 25.10.1984, p. 1124-1125.

Research output: Contribution to journalLetter