Therapy for immunologic disease. New ways of using old drugs

P. Katz

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Treatment of immunologically mediated diseases has been hampered by the lack of therapeutic agents capable of selectively altering distinct areas of the immune network. Unfortunately, most immunomodulating drugs with such capability are not selective in their suppressive effects, often causing untoward reactions such as infection. In an attempt to obviate these effects, new schemes of administering these agents so as to minimize adverse side effects and maximize benefits have been developed. Such regimens utilizing corticosteroids and certain cytotoxic drugs are proving effective. Progress with probably be limited to the devising of new protocols for existing pharmacologic agents until newer drugs are developed that can more precisely modify specific phases of the exaggerated immune reactivity characteristic of immunologically mediated diseases.

Original languageEnglish
Pages (from-to)353-360
Number of pages8
JournalPostgraduate Medicine
Volume74
Issue number4
StatePublished - Jan 1 1983
Externally publishedYes

Fingerprint

Immune System Diseases
Pharmaceutical Preparations
Adrenal Cortex Hormones
Therapeutics
Infection

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Therapy for immunologic disease. New ways of using old drugs. / Katz, P.

In: Postgraduate Medicine, Vol. 74, No. 4, 01.01.1983, p. 353-360.

Research output: Contribution to journalArticle

Katz, P. / Therapy for immunologic disease. New ways of using old drugs. In: Postgraduate Medicine. 1983 ; Vol. 74, No. 4. pp. 353-360.
@article{3941cc32cea94294bae6e152d62710e1,
title = "Therapy for immunologic disease. New ways of using old drugs",
abstract = "Treatment of immunologically mediated diseases has been hampered by the lack of therapeutic agents capable of selectively altering distinct areas of the immune network. Unfortunately, most immunomodulating drugs with such capability are not selective in their suppressive effects, often causing untoward reactions such as infection. In an attempt to obviate these effects, new schemes of administering these agents so as to minimize adverse side effects and maximize benefits have been developed. Such regimens utilizing corticosteroids and certain cytotoxic drugs are proving effective. Progress with probably be limited to the devising of new protocols for existing pharmacologic agents until newer drugs are developed that can more precisely modify specific phases of the exaggerated immune reactivity characteristic of immunologically mediated diseases.",
author = "P. Katz",
year = "1983",
month = "1",
day = "1",
language = "English",
volume = "74",
pages = "353--360",
journal = "Postgraduate Medicine",
issn = "0032-5481",
publisher = "Medquest Communications LLC",
number = "4",

}

TY - JOUR

T1 - Therapy for immunologic disease. New ways of using old drugs

AU - Katz, P.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - Treatment of immunologically mediated diseases has been hampered by the lack of therapeutic agents capable of selectively altering distinct areas of the immune network. Unfortunately, most immunomodulating drugs with such capability are not selective in their suppressive effects, often causing untoward reactions such as infection. In an attempt to obviate these effects, new schemes of administering these agents so as to minimize adverse side effects and maximize benefits have been developed. Such regimens utilizing corticosteroids and certain cytotoxic drugs are proving effective. Progress with probably be limited to the devising of new protocols for existing pharmacologic agents until newer drugs are developed that can more precisely modify specific phases of the exaggerated immune reactivity characteristic of immunologically mediated diseases.

AB - Treatment of immunologically mediated diseases has been hampered by the lack of therapeutic agents capable of selectively altering distinct areas of the immune network. Unfortunately, most immunomodulating drugs with such capability are not selective in their suppressive effects, often causing untoward reactions such as infection. In an attempt to obviate these effects, new schemes of administering these agents so as to minimize adverse side effects and maximize benefits have been developed. Such regimens utilizing corticosteroids and certain cytotoxic drugs are proving effective. Progress with probably be limited to the devising of new protocols for existing pharmacologic agents until newer drugs are developed that can more precisely modify specific phases of the exaggerated immune reactivity characteristic of immunologically mediated diseases.

UR - http://www.scopus.com/inward/record.url?scp=0020637611&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020637611&partnerID=8YFLogxK

M3 - Article

VL - 74

SP - 353

EP - 360

JO - Postgraduate Medicine

JF - Postgraduate Medicine

SN - 0032-5481

IS - 4

ER -